133095-91-7 Usage
Description
3,4,5-Trimethoxypheynylmagnesium Bromide Solution 0.5M in Tetrahydrofuran is a chemical reagent used in organic synthesis. It is a solution of 3,4,5-trimethoxypheynylmagnesium bromide in tetrahydrofuran, a common solvent in organic chemistry. This reagent is useful in the synthesis of various compounds with therapeutic potential.
Uses
Used in Pharmaceutical Industry:
3,4,5-Trimethoxypheynylmagnesium Bromide Solution 0.5M in Tetrahydrofuran is used as a reactant in the synthesis of several compounds with therapeutic potential. It plays a crucial role in the production of pharmaceuticals, contributing to the development of new drugs and therapies.
Used in Organic Synthesis:
3,4,5-Trimethoxypheynylmagnesium Bromide Solution 0.5M in Tetrahydrofuran is used as a reagent in organic synthesis for the preparation of various organic compounds. Its unique properties make it a valuable tool in the synthesis of complex molecules and the development of new chemical reactions.
Used in Research and Development:
3,4,5-Trimethoxypheynylmagnesium Bromide Solution 0.5M in Tetrahydrofuran is used as a research tool in the development of new synthetic methods and the study of reaction mechanisms. It helps researchers to understand the behavior of different chemical compounds and to design more efficient synthetic routes for the production of target molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 133095-91-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,0,9 and 5 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 133095-91:
(8*1)+(7*3)+(6*3)+(5*0)+(4*9)+(3*5)+(2*9)+(1*1)=117
117 % 10 = 7
So 133095-91-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H11O3.BrH.Mg/c1-10-7-5-4-6-8(11-2)9(7)12-3;;/h5-6H,1-3H3;1H;/q;;+1/p-1/rC9H11BrMgO3/c1-12-7-4-6(11-10)5-8(13-2)9(7)14-3/h4-5H,1-3H3
133095-91-7Relevant articles and documents
Enantioselective α-Arylation of Ketones via a Novel Cu(I)-Bis(phosphine) Dioxide Catalytic System
Escudero-Casao, Margarita,Licini, Giulia,Orlandi, Manuel
supporting information, p. 3289 - 3294 (2021/04/07)
A novel catalytic system based on copper(I) and chiral bis(phosphine) dioxides is described. This allows the arylation of silyl enol ethers to access enolizable α-arylated ketones in good yields and enantiomeric excess up to 95%. Noncyclic ketones are amenable substrates with this method, which complements other approaches based on palladium catalysis. Optimization of the ligand structure is accomplished via rational design driven by correlation analysis. Preliminary mechanistic hypotheses are also evaluated in order to identify the role of chiral bis(phosphine) dioxides.
Identification of CKD-516: A potent tubulin polymerization inhibitor with marked antitumor activity against murine and human solid tumors
Lee, Jaekwang,Kim, Soo Jin,Choi, Hojin,Kim, Young Hoon,Lim, In Taek,Yang, Hyun-Mo,Lee, Chang Sik,Kang, Hee Ryong,Ahn, Soon Kil,Moon, Seung Kee,Kim, Dal-Hyun,Lee, Sungsook,Choi, Nam Song,Lee, Kyung Joo
experimental part, p. 6337 - 6354 (2010/10/21)
Tubulin polymerization inhibitors had emerged as one of promising anticancer therapeutics because of their dual mechanism of action, i.e. apoptosis by cell-cycle arrest and VDA, vascular disrupting agent. VDAs are believed to be more efficient, less toxic