(2-isopropylphenyl)methanol

Base Information

• Chemical Name: (2-isopropylphenyl)methanol
• CAS No.: 21190-34-1
• Molecular Formula: C10H14O
• Molecular Weight: 150.221
• Hs Code.: 2906299090
• Mol file: 21190-34-1.mol

Synonyms:o-isopropylbenzyl alcohol;2-isopropyl-benzyl alcohol;2-Isopropyl-benzylalkohol;

Chemical Property of (2-isopropylphenyl)methanol

Chemical Property:

• Boiling Point: 122-123 °C(Press: 15 Torr)
• PKA: 14.35±0.10(Predicted)
• PSA: 20.23000
• Density: 0.9878 g/cm3(Temp: 25 °C)
• LogP: 2.30230
• Storage Temp.: 2-8°C

Purity/Quality:

98% ^*data from raw suppliers

(2-ISOPROPYLPHENYL)METHANOL ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2-isopropylphenyl)methanol

There total 25 articles about (2-isopropylphenyl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-isopropylbenzoic acid (2438-04-2) → (2-isopropylphenyl)methanol (21190-34-1)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 4h; Heating;

DOI:10.1021/ja00401a025

Reference yield: 95.0%

2-isopropylbenzaldehyde (6502-22-3) → (2-isopropylphenyl)methanol (21190-34-1)

Guidance literature:

With sodium tetrahydroborate; In ethanol; at 0 - 25 ℃; for 1h;

DOI:10.1016/j.bioorg.2019.103020

Reference yield: 95.0%

1-(chloromethyl)-2-isopropylbenzene (20034-71-3) → (2-isopropylphenyl)methanol (21190-34-1)

Guidance literature:

With iron(III) sulfate; water; In toluene; at 110 ℃; for 0.7h; Ionic liquid;

DOI:10.1039/c0nj00454e

upstream raw materials:

2-isopropylbenzoic acid

2-Isopropylbenzoesaeuremethylester

2-methylisopropylbenzene

1-(chloromethyl)-2-isopropylbenzene

Downstream raw materials:

1-(chloromethyl)-2-isopropylbenzene

2-isopropylbenzaldehyde

2-methylisopropylbenzene

1-(bromomethyl)-2-isopropylbenzene

Refernces

• 1、 D'Alessandro, Sarah,Alfano, Gloria,Di Cerbo, Luisa,Brogi, Simone,Chemi, Giulia,Relitti, Nicola,Brindisi, Margherita,Lamponi, Stefania,Novellino, Ettore,Campiani, Giuseppe,Gemma, Sandra,Basilico, Nicoletta,Taramelli, Donatella,Baratto, Maria Camilla,Pogni, Rebecca,Butini, Stefania. "Bridged bicyclic 2,3-dioxabicyclo[3.3.1]nonanes as antiplasmodial agents: Synthesis, structure-activity relationships and studies on their biomimetic reaction with Fe(II)". supporting information. . Retrieved 2019/06/13.
• 2、 Fedorov,Fedorova,Sheverdov,Pavlov,Eremkin. "Compounds of the menthane series. Synthesis of unsaturated primary alcohols with the o- and p-menthane skeletons". . p. 806 - 812. Retrieved 2016/07/30.