1-(bromomethyl)-2-isopropylbenzene

Base Information

• Chemical Name: 1-(bromomethyl)-2-isopropylbenzene
• CAS No.: 103324-37-4
• Molecular Formula: C10H13Br
• Molecular Weight: 213.117
• Mol file: 103324-37-4.mol

Synonyms:1-Isopropyl-2-brommethyl-benzol;1-bromomethyl-2-isopropylbenzene;2-isopropylbenzyl bromide;

Chemical Property of 1-(bromomethyl)-2-isopropylbenzene

Chemical Property:

• PSA: 0.00000
• LogP: 3.70490

Purity/Quality:

97% ^*data from raw suppliers

1-(Bromomethyl)-2-isopropylbenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(bromomethyl)-2-isopropylbenzene

There total 3 articles about 1-(bromomethyl)-2-isopropylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2-isopropylphenyl)methanol (21190-34-1) → 1-(bromomethyl)-2-isopropylbenzene (103324-37-4)

Guidance literature:

With phosphorus tribromide; In diethyl ether; at 20 ℃;

DOI:10.1021/jm020477g

Reference yield:

1-bromo-2-isopropylbenzene (7073-94-1) → 1-(bromomethyl)-2-isopropylbenzene (103324-37-4)

Guidance literature:

Multi-step reaction with 2 steps

1: n-BuLi / tetrahydrofuran; hexane / 160 °C

2: PBr₃ / diethyl ether / 20 °C

With n-butyllithium; phosphorus tribromide; In tetrahydrofuran; diethyl ether; hexane;

DOI:10.1021/jm020477g

Reference yield:

→ 1-(bromomethyl)-2-isopropylbenzene (103324-37-4)

Guidance literature:

upstream raw materials:

(2-isopropylphenyl)methanol

1-bromo-2-isopropylbenzene

Downstream raw materials:

2-isopropylbenzylzinc bromide