Bicyclo[2.2.1]heptan-1-amine (9CI)

Base Information

• Chemical Name: Bicyclo[2.2.1]heptan-1-amine (9CI)
• CAS No.: 21245-51-2
• Molecular Formula: C7H13N
• Molecular Weight: 111.18500
• Hs Code.: 2921300090
• Mol file: 21245-51-2.mol

Synonyms:1-Norbornylamine;exo-Aminonorbornane;norbornyl amine;exo-norbornyl amine;1-aminonorbornane;

Chemical Property of Bicyclo[2.2.1]heptan-1-amine (9CI)

Chemical Property:

• PSA: 26.02000
• LogP: 1.97810

Purity/Quality:

97% ^*data from raw suppliers

Bicyclo[2.2.1]hept-1-ylamine 96 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Bicyclo[2.2.1]heptan-1-amine (9CI)

There total 5 articles about Bicyclo[2.2.1]heptan-1-amine (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

norbornane-1-carboxylic acid (18720-30-4) → 1-norbornylamine (21245-51-2)

Guidance literature:

Multistep reaction; (i) NaN₃, H₂SO₄, CHCl₃, (ii) H₂O;

DOI:10.1021/jm50017a014

Reference yield:

exo,endo-2-bromobicyclo<2.2.1>heptane-1-carboxylic acid (74830-47-0) → 1-norbornylamine (21245-51-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 61 percent / tri-n-butyltin hydride

2: conc. sulfuric acid, sodium azide / CHCl₃

With sodium azide; sulfuric acid; tri-n-butyl-tin hydride; In chloroform;

DOI:10.1021/jo00296a026

Reference yield:

1-azaidobicyclo<2.2.1>heptane (65864-91-7,28673-83-8) → 1-norbornylamine (21245-51-2) + 2-azabicyclo[2.2.2]octene (95673-69-1)

Guidance literature:

In polyethylene; at -261.2 ℃; Product distribution; Irradiation;

DOI:10.1021/ja00295a038

upstream raw materials:

norbornane-1-carboxylic acid

1-azaidobicyclo<2.2.1>heptane

exo,endo-2-bromobicyclo<2.2.1>heptane-1-carboxylic acid

Downstream raw materials:

C₁₄H₁₇NO₂*ClH

trans-N-tert-Butyl-N'-1-norbornyldiazene

cis-N-tert-Butyl-N'-1-norbornyldiazene

1-Azidonorbornan