1-(4-Chloro-2-methylphenyl)-3-methylurea

Base Information

Chemical Name:1-(4-Chloro-2-methylphenyl)-3-methylurea
CAS No.:22175-20-8
Molecular Formula:C₉H₁₁ClN₂O
Molecular Weight:198.652
Hs Code.:
European Community (EC) Number:667-237-5
NSC Number:164349
DSSTox Substance ID:DTXSID80304139
Wikidata:Q82049850
Mol file:22175-20-8.mol

Synonyms:1-(4-chloro-2-methylphenyl)-3-methylurea;22175-20-8;NSC164349;SCHEMBL11416927;DTXSID80304139;AKOS024335236;NSC-164349

Suppliers and Price of 1-(4-Chloro-2-methylphenyl)-3-methylurea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 1-(4-Chloro-2-methylphenyl)-3-methylurea

Chemical Property:

Vapor Pressure:0.00419mmHg at 25°C
Boiling Point:278.7°Cat760mmHg
Flash Point:122.4°C
Density:1.245g/cm³
XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:198.0559907
Heavy Atom Count:13
Complexity:187

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=CC(=C1)Cl)NC(=O)NC

Technology Process of 1-(4-Chloro-2-methylphenyl)-3-methylurea

There total 1 articles about 1-(4-Chloro-2-methylphenyl)-3-methylurea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 22175-20-8
1-(4-chloro-2-methylphenyl)-3-methylurea

Guidance literature:: o-Acetyl-N-methylcarbamoyl-N-(2-tolyl)-hydroxylamin, HCl;

Reference yield: 54.0%

: 22175-20-8
1-(4-chloro-2-methylphenyl)-3-methylurea

: 1071-36-9
sodium cyanoacetate

: 76562-59-9
6-Amino-1-(4-chloro-2-methyl-phenyl)-3-methyl-1H-pyrimidine-2,4-dione

Guidance literature:: With sodium hydroxide; sulfuric acid; 1) acetic anhydride, 60 deg C, 2h, 2) 60 deg C, 1h;

Reference yield:

: 22175-20-8
1-(4-chloro-2-methylphenyl)-3-methylurea

: 76562-63-5
5,6-Diamino-1-(4-chloro-2-methyl-phenyl)-3-methyl-1H-pyrimidine-2,4-dione

Guidance literature:: Multi-step reaction with 3 steps

1: 54 percent / 1) H₂SO₄, 2) 20percent NaOH / 1) acetic anhydride, 60 deg C, 2h, 2) 60 deg C, 1h

2: 70 percent / NaNO₂/ acetic acid

3: 60 percent / NaHSO₃ / aq. NH₃ / 1 h / Ambient temperature

With sodium hydroxide; sulfuric acid; sodium hydrogensulfite; acetic acid; sodium nitrite; In ammonium hydroxide;