1071-36-9

Basic information

• Product Name: SODIUM CYANOACETATE
• Synonyms: SODIUM CYANOACETATE;50wt%aqueoussolution;Natriumcyanacetat;SODIUM CYANOACETATE, 50 WT% AQUEOUS SOLUTION;Acetic acid, cyano-, sodiuM salt;2-Cyanoacetic acid sodium salt
• CAS NO: 1071-36-9
• Molecular Formula: C₃H₂NO₂*Na
• Molecular Weight: 107.04
• EINECS: 213-991-1
• Mol File: 1071-36-9.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 100 °C
• Flash Point: 107.8°C
• Appearance: Clear yellow to brown/Solution
• Density: 1.32
• Vapor Pressure: 7.55E-05mmHg at 25°C
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: SODIUM CYANOACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: SODIUM CYANOACETATE(1071-36-9)
• EPA Substance Registry System: SODIUM CYANOACETATE(1071-36-9)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 1071-36-9(Hazardous Substances Data)

Usage

Chemical Properties

clear yellow to brown solution

InChI:InChI=1/C3H3NO2.Na/c4-2-1-3(5)6;/h1H2,(H,5,6);/q;+1/p-1

Upstream product

• 105-56-6 ethyl 2-cyanoacetate 
• 3792-50-5 L-aspartic acid monosodium salt 
• 372-09-8 cyanoacetic acid 

Downstream Products

• 65004-73-1 3t-(3-methoxy-4-benzyloxy-phenyl)-2-cyano-acrylic acid 
• 30842-82-1 1,5-di(o-carboxyphenyl)-3-cyanoformazane 
• 42460-57-1 3t-(3-nitro-4-methoxy-phenyl)-2-cyano-acrylic acid 
• 91106-58-0 2-cyano-3t-(2,3-dimethoxy-phenyl)-acrylic acid 
• 76562-60-2 6-amino-3-ethyl-1-phenyluracil 
• 372-09-8 cyanoacetic acid 
• 2947-61-7 (4-methylphenyl)acetonitrile 
• 459-22-3 4-fluorophenylacetonitrile 
• 7498-57-9 2-naphthaleneacetonitrile 
• 132-75-2 naphthalen-1-ylacetonitrile 
• 38746-92-8 2-[4-(methylsulfanyl)phenyl]acetonitrile 
• 16532-78-8 3-(cyanomethyl)benzonitrile 
• 621-50-1 (3-nitrophenyl)acetonitrile 
• 21192-61-0 2-(4-benzoylphenyl)acetonitrile 

Relevant articles and documents

Ruthenium-catalyzed aerobic oxidative decarboxylation of amino acids: A green, zero-waste route to biobased nitriles

Oxidative decarboxylation of amino acids into nitriles was performed using molecular oxygen as terminal oxidant and a heterogeneous ruthenium hydroxide-based catalyst. A range of amino acids was oxidized in very good yield, using water as the solvent. This journal is

Method for synthesizing drug intermediate

The invention discloses a method for synthesizing a drug intermediate. Cyano-acetate and 3,5-bis(trifluoromethyl) halogenobenzene are dissolved in a solvent and have a decarboxylation cyanomethylation reaction under the action of a palladium catalyst and an organic phosphorus ligand to obtain 2-(3,5-bis(trifluoromethyl phenyl) acetonitrile, then 2-(3,5-bis(trifluoromethyl phenyl) acetonitrile reacts with a methylation reagent to obtain 2-(3,5-bis(trifluoromethyl phenyl)-2-methyl propanenitrile, and finally cyano groups are converted into carboxyl groups with alkali to obtain the target product. The method for synthesizing the drug intermediate is easy to operate, raw materials are cheap and easy to obtain, synthesis is easy, side reactions do not happen, and the yield is high.

Decarboxylation of a Wide Range of Amino Acids with Electrogenerated Hypobromite

Bromide-assisted electrochemical decarboxylation efficiently produces valuable nitriles in high yields from a wide range of naturally occurring amino acids in a single step. Bromide salts are used as both redox mediators and supporting electrolytes in a simple one-compartment setup. As demonstrated for lysine, the selectivity of the decarboxylation can be tuned towards nitriles, amines or amides. An electrochemical system is developed that allows the selective decarboxylation of a wide range of amino acids. Valuable nitriles are obtained in high yields in a single step by using bromide salts as both redox mediators and supporting electrolytes. The product selectivity of lysine can be tuned towards nitriles, amines, or amides.