[1,2,4]Triazolo[1,5-a]pyrimidine, 5,7-dichloro-6-(2,4,6-trifluorophenyl)-

Base Information

Chemical Name:[1,2,4]Triazolo[1,5-a]pyrimidine, 5,7-dichloro-6-(2,4,6-trifluorophenyl)-
CAS No.:214707-02-5
Molecular Formula:C11H3Cl2F3N4
Molecular Weight:319.073
Hs Code.:
European Community (EC) Number:606-776-2
DSSTox Substance ID:DTXSID60453194
Nikkaji Number:J2.611.277J
Wikidata:Q82274268
Mol file:214707-02-5.mol

Synonyms:214707-02-5;5,7-dichloro-6-(2,4,6-trifluorophenyl)-[1,2,4]triazolo[1,5-a]pyrimidine;5,7-dichloro-6-(2,4,6-trifluorophenyl)[1,2,4]triazolo[1,5-a]pyrimidine;[1,2,4]Triazolo[1,5-a]pyrimidine, 5,7-dichloro-6-(2,4,6-trifluorophenyl)-;SCHEMBL3276173;DTXSID60453194;FRUHHVIOSKAPJF-UHFFFAOYSA-N;5,7-dichloro-6-(2,4,6-trifluorophenyl)-1,2,4-triazolo[1,5-a]-pyrimidine;5,7-dichloro-6-(2,4,6-trifluorophenyl)-[1,2,4]triazolo[1,5-a]-pyrimidine;5,7-dichloro-6-(2,4,6-trifluorophenyl)-1,2,4-triazolo[1,5-a]- pyrimidine

Suppliers and Price of [1,2,4]Triazolo[1,5-a]pyrimidine, 5,7-dichloro-6-(2,4,6-trifluorophenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of [1,2,4]Triazolo[1,5-a]pyrimidine, 5,7-dichloro-6-(2,4,6-trifluorophenyl)-

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:317.9686860
Heavy Atom Count:20
Complexity:355

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=C(C(=C1F)C2=C(N3C(=NC=N3)N=C2Cl)Cl)F)F

Technology Process of [1,2,4]Triazolo[1,5-a]pyrimidine, 5,7-dichloro-6-(2,4,6-trifluorophenyl)-

There total 6 articles about [1,2,4]Triazolo[1,5-a]pyrimidine, 5,7-dichloro-6-(2,4,6-trifluorophenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: bis-sodium salt of 6-(2,4,6-trifluorophenyl)-[1,2,4]triazolo[1,5-a]pyrimidine-5,7-diol

: 214707-02-5
5,7-dichloro-6-(2,4,6-trifluorophenyl)-[1,2,4]triazolo[1,5-a]pyrimidine

Guidance literature:: bis-sodium salt of 6-(2,4,6-trifluorophenyl)-[1,2,4]triazolo[1,5-a]pyrimidine-5,7-diol; With trichlorophosphate; for 16h; Heating / reflux;

With water; In water; ethyl acetate; at 5 - 15 ℃;

Reference yield:

: 214707-01-4
5,7-dihydroxy-6-(2,4,6-trifluorophenyl)[1,2,4]triazolo[1,5-a]pyrimidine

: 214707-02-5
5,7-dichloro-6-(2,4,6-trifluorophenyl)-[1,2,4]triazolo[1,5-a]pyrimidine

Guidance literature:: With trichlorophosphate; at 25 - 140 ℃; under 1800.18 - 1950.2 Torr; Product distribution / selectivity;

Reference yield:

: 262609-07-4
diethyl (2,4,6-trifluoro-phenyl)-malonate

: 214707-02-5
5,7-dichloro-6-(2,4,6-trifluorophenyl)-[1,2,4]triazolo[1,5-a]pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1.1: tributyl-amine / 2 h / 170 °C

1.2: 50 °C

2.1: trichlorophosphate / 6 h / 130 °C

With tributyl-amine; trichlorophosphate;