5-(azidomethyl)benzo[d][1,3]dioxole

Base Information

• Chemical Name: 5-(azidomethyl)benzo[d][1,3]dioxole
• CAS No.: 214783-17-2
• Molecular Formula: C8H7N3O2
• Molecular Weight: 177.162
• Mol file: 214783-17-2.mol

Synonyms:5-Azidomethyl-benzo[1,3]dioxol;(1,3-benzodioxol-5-yl)methyl azide;1,3-benzodioxol-5-ylmethyl azide;5-azidomethyl-benzo[1,3]dioxole;piperonyl azide;

Chemical Property of 5-(azidomethyl)benzo[d][1,3]dioxole

Chemical Property:

• Boiling Point: 142 °C(Press: 13 Torr)
• PSA: 68.21000
• LogP: 1.67836

Purity/Quality:

95% ^*data from raw suppliers

5-(azidomethyl)-2H-1,3-benzodioxole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-(azidomethyl)benzo[d][1,3]dioxole

There total 8 articles about 5-(azidomethyl)benzo[d][1,3]dioxole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

3,4-Methylenedioxybenzyl bromide (2606-51-1) → 5-(azidomethyl)benzo[d][1,3]dioxole (214783-17-2)

Guidance literature:

With sodium azide;

DOI:10.1021/ma301061z

Reference yield: 86.0%

piperonol (495-76-1) → 5-(azidomethyl)benzo[d][1,3]dioxole (214783-17-2)

Guidance literature:

With sodium azide; boron trifluoride diethyl etherate; In 1,4-dioxane; at 80 - 90 ℃; for 4h;

DOI:10.1016/s0040-4039(98)01602-5

Reference yield: 70.0%

1,3-benzodioxol-5-ylmethyl amine (2620-50-0) → 5-(azidomethyl)benzo[d][1,3]dioxole (214783-17-2)

Guidance literature:

With triflic azide; copper(II) sulfate; triethylamine; In methanol; dichloromethane; water; at 20 ℃; Cooling with ice;

DOI:10.1002/anie.201609655

upstream raw materials:

piperonol

sulfuric acid

(1,3-benzodioxol-5-yl)methyl 4-methylbenzenesulfonate

3,4-Methylenedioxybenzyl bromide

Downstream raw materials:

piperonylonitrile

3,4-methylenedioxybenzylamine hydrochloride

1,3-benzodioxol-5-ylmethyl amine

N-methylpiperonylamine