Piperonyl alcohol

Base Information

• Chemical Name: Piperonyl alcohol
• CAS No.: 495-76-1
• Deprecated CAS: 659726-31-5,2169723-84-4
• Molecular Formula: C8H8O3
• Molecular Weight: 152.15
• Hs Code.: 29329970
• European Community (EC) Number: 207-808-4
• NSC Number: 26265
• UNII: 4163K563GS
• DSSTox Substance ID: DTXSID3060089
• Nikkaji Number: J25.458D
• Wikidata: Q27258401
• Mol file: 495-76-1.mol

Synonyms:3,4-methylenedioxybenzyl alcohol;piperonyl alcohol

Chemical Property of Piperonyl alcohol

Chemical Property:

• Appearance/Colour: White crystals or crystalline powder
• Vapor Pressure: 0.00161mmHg at 25°C
• Melting Point: 50-54 °C(lit.)
• Refractive Index: 1.594
• Boiling Point: 282.2 °C at 760 mmHg
• PKA: 14.36±0.10(Predicted)
• Flash Point: 124.5 °C
• PSA: 38.69000
• Density: 1.329 g/cm³
• LogP: 0.90760
• Storage Temp.: Inert atmosphere,Room Temperature
• Water Solubility.: soluble
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 152.047344113
• Heavy Atom Count: 11
• Complexity: 137

Purity/Quality:

99%min ^*data from raw suppliers

Piperonyl alcohol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Other Classes -> Alcohols and Polyols, Other
• Canonical SMILES: C1OC2=C(O1)C=C(C=C2)CO
• Uses: Piperonyl Alcohol acts as an anti-oxidant on lipid peroxidation through inhibition. It is also used as a reagent in improving stability and antioxidant characteristics of sesame oil through spray-drie d emulsions. Piperonyl Alcohol acts as an anti-oxidant on lipid peroxidation through inhibition. It is also used as a reagent in improving stability and antioxidant characteristics of sesame oil through spray-dried emulsions.

Technology Process of Piperonyl alcohol

There total 74 articles about Piperonyl alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

piperonal (120-57-0,30024-74-9) → piperonol (495-76-1)

Guidance literature:

With diisopropoxytitanium(III) tetrahydroborate; In dichloromethane; at -20 ℃; for 0.133333h;

DOI:10.1021/jo951313t

Reference yield: 99.0%

piperonyl acetate (326-61-4) → piperonol (495-76-1)

Guidance literature:

With methanol; potassium permanganate; at 25 ℃; chemoselective reaction;

DOI:10.1039/d0nj04321d

Reference yield: 99.0%

C14H19BO5 → piperonol (495-76-1)

Guidance literature:

With silica gel; In hexane; ethyl acetate;

DOI:10.1002/anie.201607579

upstream raw materials:

piperonal

ethanol

2-(methyl-piperonyl-amino)-ethanol

acetic anhydride

Downstream raw materials:

5-(1-butoxy-ethoxymethyl)-benzo[1,3]dioxole

benzo[d][1,3]dioxol-5-ylmethyl benzoate

4-methoxy-benzoic acid piperonyl ester

3,4-methylenedioxybenzyl isobutanoate

Refernces

• 1、 Cabral, Marise M.O.,Garcia, Eloi S.,Gottlieb, Otto R.,Kelecom, Alphonse. "Degradation of the neolignan, burchellin in the hemolymph of the bloodsucking insect Rhodnius prolixus". . p. 59 - 63. Retrieved 2008.
• 2、 Gholap, Sandeep Suryabhan,Dakhil, Abdullah Al,Chakraborty, Priyanka,Li, Huaifeng,Dutta, Indranil,Das, Pradip K.,Huang, Kuo-Wei. "Efficient and chemoselective hydrogenation of aldehydes catalyzed by well-defined PN3-pincer manganese(ii) catalyst precursors: An application in furfural conversion". supporting information. p. 11815 - 11818. Retrieved 2021/11/30.
• 3、 -. "Method for synthesizing piperonyl alcohol through catalytic hydrogenation". Paragraph 0024-0035. . Retrieved 2021/02/10.