6-(2-METHOXY-PHENYL)-1,3-DIHYDRO-INDOL-2-ONE

Base Information

Chemical Name:6-(2-METHOXY-PHENYL)-1,3-DIHYDRO-INDOL-2-ONE
CAS No.:215433-87-7
Molecular Formula:C15H13NO2
Molecular Weight:239.274
Hs Code.:
Mol file:215433-87-7.mol

Synonyms:6-(2-methoxyphenyl)-2-oxindole;6-(2-Methoxy-phenyl)-1,3-dihydro-indol-2-one;6-(2-methoxyphen-1-yl)oxindole;6-(2-methoxyphenyl)-2-indolinone;6-(2-Methoxyphenyl)-1,3-dihydroindol-2-one;

Suppliers and Price of 6-(2-METHOXY-PHENYL)-1,3-DIHYDRO-INDOL-2-ONE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
6-(2-methoxy-phenyl)-1,3-dihydro-indol-2-one 95
25g
$ 3588.00

Labseeker
6-(2-methoxy-phenyl)-1,3-dihydro-indol-2-one 95
10g
$ 2933.00

Labseeker
6-(2-methoxy-phenyl)-1,3-dihydro-indol-2-one 95
5g
$ 2200.00

Total 1 raw suppliers

Chemical Property of 6-(2-METHOXY-PHENYL)-1,3-DIHYDRO-INDOL-2-ONE

Chemical Property:

PSA：38.33000
LogP:2.99480

Purity/Quality:

98% ^*data from raw suppliers

6-(2-methoxy-phenyl)-1,3-dihydro-indol-2-one 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6-(2-METHOXY-PHENYL)-1,3-DIHYDRO-INDOL-2-ONE

There total 7 articles about 6-(2-METHOXY-PHENYL)-1,3-DIHYDRO-INDOL-2-ONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 215433-94-6
2'-methoxy-3-nitrobiphenyl-4-acetic acid

: 215433-87-7
6-(2-methoxy-phenyl)-2-oxo-1,2-dihydro-indole

Guidance literature:: With iron; acetic acid; at 100 ℃; for 3h;
DOI:10.1021/jm9904295

Reference yield:

: 7439-89-6
iron

: 215433-94-6
2'-methoxy-3-nitrobiphenyl-4-acetic acid

: 215433-87-7
6-(2-methoxy-phenyl)-2-oxo-1,2-dihydro-indole

Guidance literature:: In hexane; acetic acid; ethyl acetate;

Reference yield:

: 364-73-8
4-Bromo-1-fluoro-2-nitrobenzene

: 215433-87-7
6-(2-methoxy-phenyl)-2-oxo-1,2-dihydro-indole

Guidance literature:: Multi-step reaction with 4 steps

1.1: (Ph₃P)4Pd; NaHCO₃ / toluene / 2 h / Heating

2.1: NaH; DMSO / 0.25 h / 100 °C

2.2: dimethylsulfoxide / 2 h / 100 °C

3.1: 9.8 g / 6 N aq. HCl / 24 h / 100 °C

4.1: Fe; AcOH / 3 h / 100 °C

With hydrogenchloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; iron; sodium hydride; sodium hydrogencarbonate; acetic acid; dimethyl sulfoxide; In toluene; 1.1: Suzuki coupling / 2.1: Metallation / 2.2: Condensation / 3.1: hydrolytic decarboxylation / 4.1: reductive cyclization;
DOI:10.1021/jm9904295