[4-(Benzyloxy)-3,5-dimethoxyphenyl]methanol

Base Information

Chemical Name:[4-(Benzyloxy)-3,5-dimethoxyphenyl]methanol
CAS No.:2176-18-3
Molecular Formula:C16H18O4
Molecular Weight:274.317
Hs Code.:
DSSTox Substance ID:DTXSID90553378
Wikidata:Q82433942

Synonyms:2176-18-3;[4-(Benzyloxy)-3,5-dimethoxyphenyl]methanol;SCHEMBL7511997;DTXSID90553378;AKOS009116081

Suppliers and Price of [4-(Benzyloxy)-3,5-dimethoxyphenyl]methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of [4-(Benzyloxy)-3,5-dimethoxyphenyl]methanol

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:274.12050905
Heavy Atom Count:20
Complexity:251

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=CC(=C1OCC2=CC=CC=C2)OC)CO

Technology Process of [4-(Benzyloxy)-3,5-dimethoxyphenyl]methanol

There total 14 articles about [4-(Benzyloxy)-3,5-dimethoxyphenyl]methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 6527-32-8
4-(benzyloxy)-3,5-dimethoxybenzaldehyde

: 2176-18-3
4-benzyloxy-3,5-dimethoxybenzyl alcohol

Guidance literature:: With sodium tetrahydroborate;
DOI:10.3987/R-1987-05-1169

Reference yield: 94.0%

: 27065-65-2
methyl 4-benzyloxy-3,5-dimethoxybenzoate

: 2176-18-3
4-benzyloxy-3,5-dimethoxybenzyl alcohol

Guidance literature:: With lithium aluminium tetrahydride; In diethyl ether; at 0 ℃;
DOI:10.1021/np0200257

Reference yield:

: 134-96-3
syringic aldehyde

: 2176-18-3
4-benzyloxy-3,5-dimethoxybenzyl alcohol

Guidance literature:: Multi-step reaction with 2 steps

1: triphenylphosphine; diisopropyl azo-dicarboxylate / tetrahydrofuran / 0 °C

2: sodium borohydride / methanol

With sodium tetrahydroborate; di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; methanol; 1: Mitsunobu coupling;
DOI:10.1021/ol036300d