1H-Pyrazole-5-carboxamide, 1-(3-amino-1,2-benzisoxazol-5-yl)-N-[2-fluoro-4-(2-methyl-1H-imidazol- 1-yl)phenyl]-3-(trifluoromethyl)-, mono(trifluoroacetate)

Base Information

Chemical Name:1H-Pyrazole-5-carboxamide, 1-(3-amino-1,2-benzisoxazol-5-yl)-N-[2-fluoro-4-(2-methyl-1H-imidazol- 1-yl)phenyl]-3-(trifluoromethyl)-, mono(trifluoroacetate)
CAS No.:218299-86-6
Molecular Formula:C22H15F4N7O2.C2HF3O2
Molecular Weight:599.424
Hs Code.:

1H-Pyrazole-5-carboxamide,
1-(3-amino-1,2-benzisoxazol-5-yl)-N-[2-fluoro-4-(2-methyl-1H-imidazol-
1-yl)phenyl]-3-(trifluoromethyl)-, mono(trifluoroacetate)

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Chemical Property of 1H-Pyrazole-5-carboxamide, 1-(3-amino-1,2-benzisoxazol-5-yl)-N-[2-fluoro-4-(2-methyl-1H-imidazol- 1-yl)phenyl]-3-(trifluoromethyl)-, mono(trifluoroacetate)

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Technology Process of 1H-Pyrazole-5-carboxamide, 1-(3-amino-1,2-benzisoxazol-5-yl)-N-[2-fluoro-4-(2-methyl-1H-imidazol- 1-yl)phenyl]-3-(trifluoromethyl)-, mono(trifluoroacetate)

There total 1 articles about 1H-Pyrazole-5-carboxamide, 1-(3-amino-1,2-benzisoxazol-5-yl)-N-[2-fluoro-4-(2-methyl-1H-imidazol- 1-yl)phenyl]-3-(trifluoromethyl)-, mono(trifluoroacetate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

: 218301-88-3
2-Fluoro-4-(2-methyl-imidazol-1-yl)-phenylamine

: 218301-86-1
1-(3'-aminobenzisoxazol-5'-yl)-3-trifluoromethyl-5-pyrazolecarboxylic acid

: 218299-86-6
1-(3'-aminobenzisoxazol-5'-yl)-3-trifluoromethyl-5-[(4'-(2''-methylimidazol-1''-yl)-2'-fluorophenyl)aminocarbonyl]pyrazole TFA salt

Guidance literature:: With N-ethyl-N,N-diisopropylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate; In DMF (N,N-dimethyl-formamide); at 20 - 75 ℃; for 16.5h;