218301-88-3

Basic information

• Product Name: 2-FLUORO-4-(2-METHYL-IMIDAZOL-1-YL)-PHENYLAMINE
• Synonyms: 2-FLUORO-4-(2-METHYL-IMIDAZOL-1-YL)-PHENYLAMINE
• CAS NO: 218301-88-3
• Molecular Formula: C₁₀H₁₀FN₃
• Molecular Weight: 191.2049032
• Mol File: 218301-88-3.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-FLUORO-4-(2-METHYL-IMIDAZOL-1-YL)-PHENYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-FLUORO-4-(2-METHYL-IMIDAZOL-1-YL)-PHENYLAMINE(218301-88-3)
• EPA Substance Registry System: 2-FLUORO-4-(2-METHYL-IMIDAZOL-1-YL)-PHENYLAMINE(218301-88-3)

Safety Data

• Hazardous Substances Data: 218301-88-3(Hazardous Substances Data)

Upstream product

• 693-98-1 2-methylimidazole 
• 218301-87-2 4-(tert-butoxycarbonylamino)-3-fluorophenylboronic acid 
• 29632-74-4 2-fluro-4-iodoaniline 

Downstream Products

• 218299-53-7 1-(3'-aminobenzisoxazol-5'-yl)-3-ethyl-5-[[4-(2'-methylimidazol-1'-yl)-2-fluorophenyl]aminocarbonyl]pyrazole TFA salt 
• 218299-86-6 1-(3'-aminobenzisoxazol-5'-yl)-3-trifluoromethyl-5-[(4'-(2''-methylimidazol-1''-yl)-2'-fluorophenyl)aminocarbonyl]pyrazole TFA salt 
• 754193-49-2 1-(3'-cyano-4'-fluorophenyl)-3-trifluoromethyl-N-[2-fluoro-4-[(2'-methyl)imidazol-1-yl]phenyl]-1H-pyrazole-5-carboxyamide 

Relevant articles and documents

NOVEL GUANIDINE MIMICS AS FACTOR Xa INHIBITORS

The present application describes nitrogen containing heteroaromatics and derivatives thereof of formula (I) or pharmaceutically acceptable salt forms thereof, wherein rings D-E represent guanidine mimics, which are useful as inhibitors of factor Xa.

Guanidine mimics as factor Xa inhibitors

The present application describes nitrogen containing heteroaromatics and derivatives thereof of formula I: or pharmaceutically acceptable salt forms thereof, wherein rings D—E represent guanidine mimics, which are useful as inhibitors of factor Xa.

Efficient ligand-mediated ullmann coupling of anilnies and azoles

The present invention provides of method of preparing phenyl-substituted azoles. This method uses an efficient ligand-accelerated Ullmann coupling reaction of anilines with azoles. The coupling products are useful for preparing factor Xa inhibitors.