2-[3-(Benzyloxy)-2,4-dimethoxyphenyl]ethan-1-amine

Base Information

Chemical Name:2-[3-(Benzyloxy)-2,4-dimethoxyphenyl]ethan-1-amine
CAS No.:21882-90-6
Molecular Formula:C17H21NO3
Molecular Weight:287.359
Hs Code.:
DSSTox Substance ID:DTXSID30557830
Wikidata:Q82439861
Mol file:21882-90-6.mol

Synonyms:21882-90-6;2-[3-(Benzyloxy)-2,4-dimethoxyphenyl]ethan-1-amine;SCHEMBL8043020;DTXSID30557830

Suppliers and Price of 2-[3-(Benzyloxy)-2,4-dimethoxyphenyl]ethan-1-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2-[3-(Benzyloxy)-2,4-dimethoxyphenyl]ethan-1-amine

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:287.15214353
Heavy Atom Count:21
Complexity:281

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C(=C(C=C1)CCN)OC)OCC2=CC=CC=C2

Technology Process of 2-[3-(Benzyloxy)-2,4-dimethoxyphenyl]ethan-1-amine

There total 11 articles about 2-[3-(Benzyloxy)-2,4-dimethoxyphenyl]ethan-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 121949-62-0
3-benzyloxy-2,4-dimethoxy-β-nitrostyrene

: 21882-90-6
2-(3-benzyloxy-2,4-dimethoxyphenyl)ethylamine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 2h; Heating;
DOI:10.1002/jhet.5570250557

Reference yield: 82.0%

: 866082-86-2
C₁₇H₁₇NO₃

: 21882-90-6
2-(3-benzyloxy-2,4-dimethoxyphenyl)ethylamine

Guidance literature:: With borane-THF; for 18h;

Reference yield:

: 14588-61-5
4-benzyloxy-3,5-dimethoxybenzoic acid chloride

: 21882-90-6
2-(3-benzyloxy-2,4-dimethoxyphenyl)ethylamine

Guidance literature:: Multi-step reaction with 6 steps

1: aq. NaN₃ / acetone

2: (i) (heating), (ii) aq. NaOH

3: (i) (diazotization), (ii) (iodination)

4: aq. HCl, AcOH

6: LiAlH₄

With hydrogenchloride; lithium aluminium tetrahydride; sodium azide; acetic acid; In acetone;
DOI:10.1021/jo01264a030