24,25,26-Trinoroleanan-3-one,5,9,13-trimethyl-, (4a,5b,8a,9b,10a,13a,14b)-

Base Information

• Chemical Name: 24,25,26-Trinoroleanan-3-one,5,9,13-trimethyl-, (4a,5b,8a,9b,10a,13a,14b)-
• CAS No.: 19865-96-4
• Molecular Formula: C30H50 O
• Molecular Weight: 426.726
• Mol file: 19865-96-4.mol

Synonyms:D:A-Friedo-4bH-oleanan-3-one (8CI);D:A-Friedooleanan-3-one, (4a)-; 3(2H)-Picenone, eicosahydro-4,4a,6b,8a,11,11,12b,14a-octamethyl-,(4S,4aS,6aS,6bR,8aR,12aR,12bS,14aS,14bS)-; 4-Epifriedelin; 4-epi-Friedelin;Isofriedelin; [4S-(4a,4ab,6aa,6bb,8ab,12ab,12ba,14ab,14ba)]-Eicosahydro-4,4a,6b,8a,11,11,12b,14a-octamethyl-3(2H)-picenone

Chemical Property of 24,25,26-Trinoroleanan-3-one,5,9,13-trimethyl-, (4a,5b,8a,9b,10a,13a,14b)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 24,25,26-Trinoroleanan-3-one,5,9,13-trimethyl-, (4a,5b,8a,9b,10a,13a,14b)-

There total 10 articles about 24,25,26-Trinoroleanan-3-one,5,9,13-trimethyl-, (4a,5b,8a,9b,10a,13a,14b)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

zeylanol acetate (88530-45-4) → friedelin (559-74-0,19865-96-4,34539-66-7,60268-94-2)

Guidance literature:

With lithium 2-aminoethylamide;

DOI:10.1016/S0040-4039(01)90339-9

Reference yield: 42.7%

epifriedelanol (5085-72-3,7506-18-5,16844-71-6,105370-95-4) → friedelin (559-74-0) + 4-epi-friedelin (19865-96-4) + 3,4-secofriedelan-3 <*> 4-olide (29621-75-8)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In chloroform; for 6h; Heating;

DOI:10.1246/cl.1985.167

Reference yield:

kokzeylanol (78835-10-6) → friedelin (559-74-0,19865-96-4,34539-66-7,60268-94-2)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine

2: Li-(CH₂NH₂)2, 2.)CrO₃ / 1.)ethylene diamine, reflux, 30 min.; 2.)pyridine, 25 deg C_.

With chromium(VI) oxide; lithium 2-aminoethylamide; In pyridine;

DOI:10.1016/S0040-4039(01)90339-9

upstream raw materials:

zeylanol acetate

kokzeylanol diacetate

kokzeylanol

epifriedelanol

Downstream raw materials:

friedelin

3,4-secofriedelan-3 <*> 4-olide

epifriedelanol

3-hydroxy-D:A-friedoolean-3-en-2-one

Refernces

• 1、 Kikuchi,Takayama,Toyoda,et al.. "Studies on the neutral constituents of Pachysandra terminalis Sieb. et Zucc. V. Structures of pachysandiol B and pachysonol, new friedelin type triterpenes". . p. 2243 - 2251. Retrieved 1973.
• 2、 Gunatilaka, Leslei A. A.,Nanayakkara, Dhammika, N. P.,Sultanbawa, Uvais, M.. "STRUCTURES OF KOKZEYLANOL AND KOKZEYLANONOL". . p. 1425 - 1428. Retrieved 2007/10/02.