Technology Process of Hydrazinecarboxylic acid, 2-(3-cyano-4-hydroxybenzoyl)-,
1,1-dimethylethyl ester
There total 3 articles about Hydrazinecarboxylic acid, 2-(3-cyano-4-hydroxybenzoyl)-,
1,1-dimethylethyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
N-ethyl-N,N-diisopropylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate;
In
dichloromethane; N,N-dimethyl-formamide;
at 0 - 5 ℃;
for 24h;
DOI:10.1021/jm0208572
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 44 percent / iodine monochloride; AcOH / 65 °C
2: 73 percent / CuCN / dimethylformamide / 16 h / 100 - 110 °C
3: 84 percent / KOH / tetrahydrofuran / 20 °C
4: 56 percent / diisopropylethylamine; bromotrispyrrolidinophosphonium hexafluorophosphate / CH2Cl2; dimethylformamide / 24 h / 0 - 5 °C
With
potassium hydroxide; Iodine monochloride; acetic acid; N-ethyl-N,N-diisopropylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm0208572
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 84 percent / KOH / tetrahydrofuran / 20 °C
2: 56 percent / diisopropylethylamine; bromotrispyrrolidinophosphonium hexafluorophosphate / CH2Cl2; dimethylformamide / 24 h / 0 - 5 °C
With
potassium hydroxide; N-ethyl-N,N-diisopropylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm0208572
