N-Hydroxy-N''-(4-methoxyphenyl)guanidine

Base Information

Chemical Name:N-Hydroxy-N''-(4-methoxyphenyl)guanidine
CAS No.:219924-60-4
Molecular Formula:C8H11N3O2
Molecular Weight:181.194
Hs Code.:
DSSTox Substance ID:DTXSID90455828
Nikkaji Number:J1.664.253C
ChEMBL ID:CHEMBL289821
Mol file:219924-60-4.mol

Synonyms:219924-60-4;N-Hydroxy-N''-(4-methoxyphenyl)guanidine;CHEMBL289821;DTXSID90455828;AKOS017475096;1-(4-Methoxyphenyl)-2-hydroxyguanidine

Suppliers and Price of N-Hydroxy-N''-(4-methoxyphenyl)guanidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of N-Hydroxy-N''-(4-methoxyphenyl)guanidine

Chemical Property:

XLogP3:0.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:181.085126602
Heavy Atom Count:13
Complexity:176

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)N=C(N)NO

Technology Process of N-Hydroxy-N''-(4-methoxyphenyl)guanidine

There total 3 articles about N-Hydroxy-N''-(4-methoxyphenyl)guanidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 506-68-3
bromocyane

: 104-94-9
4-methoxy-aniline

: 219924-60-4
N-(4-methoxy)phenyl-N'-hydroxyguanidine

Guidance literature:: With hydroxylamine hydrochloride;
DOI:10.1007/s12039-014-0751-4

Reference yield:

: 13519-16-9
N-(4-methoxyphenyl)cyanamide

: 219924-60-4
N-(4-methoxy)phenyl-N'-hydroxyguanidine

Guidance literature:: With hydroxylamine hydrochloride; potassium carbonate; In ethanol; at 20 ℃; for 5h;
DOI:10.1016/S0968-0896(02)00155-4

Reference yield:

: 104-94-9
4-methoxy-aniline

: 219924-60-4
N-(4-methoxy)phenyl-N'-hydroxyguanidine

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / CH₂Cl₂ / 10 h / 20 °C

2: NH₂OH*HCl; K₂CO₃ / ethanol / 5 h / 20 °C

With hydroxylamine hydrochloride; potassium carbonate; triethylamine; In ethanol; dichloromethane;
DOI:10.1016/S0968-0896(02)00155-4