5-fluoro-2-[(4-pyridin-2-ylpiperazin-1-yl)methyl]-1H-indole

Base Information

Chemical Name:5-fluoro-2-[(4-pyridin-2-ylpiperazin-1-yl)methyl]-1H-indole
CAS No.:220941-93-5
Molecular Formula:C18H19FN4
Molecular Weight:310.36900
Hs Code.:
UNII:WX4CVT9DYH
DSSTox Substance ID:DTXSID70430875
Nikkaji Number:J1.436.629F
Wikipedia:CP-226,269
Wikidata:Q5013576
Pharos Ligand ID:27ZMJQ723NYB
ChEMBL ID:CHEMBL77395
Mol file:220941-93-5.mol

Synonyms:CP-226269;220941-93-5;CP 226269;5-fluoro-2-[(4-pyridin-2-ylpiperazin-1-yl)methyl]-1H-indole;CP-226,269;WX4CVT9DYH;5-Fluoro-2-(4-pyridin-2-yl-piperazin-1-ylmethyl)-1H-indole;CHEMBL77395;CP226269;5-fluoro-2-[[4-(2-pyridinyl)-1-piperazinyl]methyl]-1H-indole;5-Fluoro-2-((4-(2-pyridinyl)-1-piperazinyl)methyl)-1H-indole;5-Fluoro-2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-indole;5-Fluoro-2-((4-pyridin-2-ylpiperazin-1-yl)methyl)-1H-indole;1H-Indole, 5-fluoro-2-((4-(2-pyridinyl)-1-piperazinyl)methyl)-;UNII-WX4CVT9DYH;D0K3UL;GTPL973;SCHEMBL4814827;DTXSID70430875;PQOIDBZLMJMYCD-UHFFFAOYSA-N;HMS3263O08;VIA94193;Tox21_501113;BDBM50145073;AKOS040748166;CCG-222417;NCGC00261798-01;NCGC00386574-01;HY-116082;CS-0063736;FT-0665215;E98764;CP-226269, >=98% (HPLC);Q5013576;2-[4-(2-Pyridyl)piperazinomethyl]-5-fluoro-1H-indole

Suppliers and Price of 5-fluoro-2-[(4-pyridin-2-ylpiperazin-1-yl)methyl]-1H-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
CP-226269
100mg
$ 1230.00

TRC
CP-226269
10mg
$ 155.00

Sigma-Aldrich
CP-226269 ≥98% (HPLC)
5mg
$ 110.00

Sigma-Aldrich
CP-226269 ≥98% (HPLC)
25mg
$ 427.00

Medical Isotopes, Inc.
CP-226269
100 mg
$ 2280.00

American Custom Chemicals Corporation
CP-226269 95.00%
100MG
$ 2055.90

American Custom Chemicals Corporation
CP-226269 95.00%
10MG
$ 762.30

American Custom Chemicals Corporation
CP-226269 95.00%
5MG
$ 242.00

Total 5 raw suppliers

Chemical Property of 5-fluoro-2-[(4-pyridin-2-ylpiperazin-1-yl)methyl]-1H-indole

Chemical Property:

PSA：35.16000
LogP:3.02710
Storage Temp.:?20°C
Solubility.:DMSO: >10mg/mL
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:310.15937479
Heavy Atom Count:23
Complexity:385

Purity/Quality:

98% ^*data from raw suppliers

CP-226269 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1CC2=CC3=C(N2)C=CC(=C3)F)C4=CC=CC=N4
Uses CP-226269 is a D4 dopamine receptor agonist with EC50 of 32 nM for use in treating sexual dysfunction.

Technology Process of 5-fluoro-2-[(4-pyridin-2-ylpiperazin-1-yl)methyl]-1H-indole

There total 6 articles about 5-fluoro-2-[(4-pyridin-2-ylpiperazin-1-yl)methyl]-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%