Mercaptomethanol

Base Information

• Chemical Name: Mercaptomethanol
• CAS No.: 22322-29-8
• Molecular Formula: CH4OS
• Molecular Weight: 64.1082
• DSSTox Substance ID: DTXSID40548037
• Nikkaji Number: J751.202C
• Wikidata: Q82426619
• Mol file: 22322-29-8.mol

Synonyms:mercaptomethanol;Sulfanylmethanol;22322-29-8;DTXSID40548037;GXDPEHGCHUDUFE-UHFFFAOYSA-N

Chemical Property of Mercaptomethanol

Chemical Property:

• Boiling Point: 136.2±23.0 °C(Predicted)
• PSA: 59.03000
• Density: 1.132±0.06 g/cm3(Predicted)
• LogP: -0.13400
• XLogP3: -0.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 63.99828592
• Heavy Atom Count: 3
• Complexity: 4.8

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(O)S

Technology Process of Mercaptomethanol

There total 4 articles about Mercaptomethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-<2-<(2-chloroethyl)sulfinyl-18O>-2,2-dimethylethyl>-3-cyclohexyl-1-nitrosourea (83984-34-3) → 2,3-Dimethyl-2-butene (563-79-1) + thioacetone (4756-05-2) + chloroethylene (75-01-4,9002-86-2) + mercaptomethanol (22322-29-8) + 2-<(2-chloroethyl)thio>-2-methylpropanal-18O + isobutene (115-11-7,15220-85-6)

Guidance literature:

With water; at 37 ℃; in 40 mM potassium phosphate buffer (pH 7.2);

DOI:10.1021/ja00273a042

Reference yield:

1-<2-<(2-chloroethyl)sulfinyl>ethyl>-3-cyclohexyl-1-nitrosourea (73944-54-4) → chloroethylene (75-01-4,9002-86-2) + mercaptomethanol (22322-29-8)

Guidance literature:

With water; at 37 ℃; in 40mM potassium phosphate buffer (pH 7.2);

DOI:10.1021/ja00273a042

Reference yield:

glycolonitrile (107-16-4) → ethane-1,1-diol (4433-56-1) + glycolaldehyde hydrate (40460-44-4) + acetaldehyde (75-07-0,9002-91-9) + mercaptomethanol (22322-29-8)

Guidance literature:

With sodium dihydrogenphosphate dihydrate; sodium monohydrogensulphide hydrate; water; copper(l) cyanide; In water-d2; for 2h; pH=6.8 - 7; Irradiation; Inert atmosphere;

DOI:10.1002/anie.201300321

upstream raw materials:

1-<2-<(2-chloroethyl)sulfinyl>ethyl>-3-cyclohexyl-1-nitrosourea

1-<2-<(2-chloroethyl)sulfinyl-18O>-2,2-dimethylethyl>-3-cyclohexyl-1-nitrosourea

glycolonitrile

Downstream raw materials:

hydroxymethyl phenyl sulfide