2-Fluorophenoxyacetonitrile

Base Information

Chemical Name:2-Fluorophenoxyacetonitrile
CAS No.:22361-61-1
Molecular Formula:C7H6BrNO4S
Molecular Weight:151.13800
Hs Code.:2935009090
DSSTox Substance ID:DTXSID80568153
Wikidata:Q82454324
Mol file:22361-61-1.mol

Synonyms:2-Fluorophenoxyacetonitrile;137988-23-9;2-(2-Fluorophenoxy)acetonitrile;(2-Fluorophenoxy)acetonitrile;Acetonitrile, (2-fluorophenoxy)- (9CI);Acetonitrile, 2-(2-fluorophenoxy)-;Acetonitrile, (2-fluorophenoxy)-;SCHEMBL3256218;DTXSID80568153;2-(2-Fluorophenoxy)-acetonitrile;QAYDDGNSGGDTDG-UHFFFAOYSA-N;MFCD09941337;AKOS000182512;AS-32012;SY010999;CS-0309083;EN300-155907;J-505623

Suppliers and Price of 2-Fluorophenoxyacetonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
2-Bromo-5-sulfamoylbenzoic acid
1 g
$ 437.00

Crysdot
2-Bromo-5-sulfamoylbenzoicacid 95+%
5g
$ 550.00

Apolloscientific
2-Bromo-5-sulfamoylbenzoicacid
1g
$ 396.00

American Custom Chemicals Corporation
5-(AMINOSULFONYL)-2-BROMOBENZOIC ACID 95.00%
2.5G
$ 1337.31

American Custom Chemicals Corporation
5-(AMINOSULFONYL)-2-BROMOBENZOIC ACID 95.00%
1G
$ 336.00

Alichem
2-Bromo-5-sulfamoylbenzoicacid
5g
$ 577.20

AK Scientific
5-(Aminosulfonyl)-2-bromobenzoicacid
5g
$ 1215.00

Total 7 raw suppliers

Chemical Property of 2-Fluorophenoxyacetonitrile

Chemical Property:

PSA：33.02000
LogP:1.72808
XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:151.043341977
Heavy Atom Count:11
Complexity:163

Purity/Quality:

97% ^*data from raw suppliers

2-Bromo-5-sulfamoylbenzoic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)OCC#N)F

Technology Process of 2-Fluorophenoxyacetonitrile

There total 2 articles about 2-Fluorophenoxyacetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3285-31-2
2-bromo-5-(chlorosulfonyl)benzoic acid

: 22361-61-1
C₇H₆BrNO₄S

Guidance literature:: With ammonia; Cooling with ice;

Reference yield:

: 88-65-3
2-bromobenzoic-acid

: 22361-61-1
C₇H₆BrNO₄S

Guidance literature:: Multi-step reaction with 2 steps

1: chlorosulfonic acid / 135 - 140 °C

2: ammonia / Cooling with ice

With chlorosulfonic acid; ammonia;

Reference yield:

: 22361-61-1
C₇H₆BrNO₄S

: C₁₈H₂₆N₂O₈S

Guidance literature:: Multi-step reaction with 8 steps

1: thionyl chloride / 20 °C

2: triethylamine; dmap / dichloromethane / 20 °C

3: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 0 °C

4: triethylamine / tetrahydrofuran / 4 h / 20 °C / Cooling with ice

5: sodium azide / N,N-dimethyl-formamide / 3 h / 60 °C

6: triphenylphosphine / tetrahydrofuran / 3 h / 20 °C

7: triethylamine; dmap / 20 °C

8: n-butyllithium / tetrahydrofuran / 2 h / -70 °C / Inert atmosphere

With dmap; lithium aluminium tetrahydride; n-butyllithium; thionyl chloride; sodium azide; triethylamine; triphenylphosphine; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;