Technology Process of Benzoyl chloride, 4-(fluoromethyl)- (9CI)
There total 4 articles about Benzoyl chloride, 4-(fluoromethyl)- (9CI) which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: ethanol; sodium tetrahydroborate / 1.5 h / 0 - 5 °C
2: diethylamino-sulfur trifluoride / dichloromethane / 0 - 20 °C / Cooling with ice
3: sodium hydroxide; water / methanol / 16 h / 20 °C
4: N,N-dimethyl-formamide; oxalyl dichloride / dichloromethane / 64 h / 20 °C
With
sodium tetrahydroborate; oxalyl dichloride; ethanol; diethylamino-sulfur trifluoride; water; N,N-dimethyl-formamide; sodium hydroxide;
In
methanol; dichloromethane;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium hydroxide; water / methanol / 16 h / 20 °C
2: N,N-dimethyl-formamide; oxalyl dichloride / dichloromethane / 64 h / 20 °C
With
oxalyl dichloride; water; N,N-dimethyl-formamide; sodium hydroxide;
In
methanol; dichloromethane;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: diethylamino-sulfur trifluoride / dichloromethane / 0 - 20 °C / Cooling with ice
2: sodium hydroxide; water / methanol / 16 h / 20 °C
3: N,N-dimethyl-formamide; oxalyl dichloride / dichloromethane / 64 h / 20 °C
With
oxalyl dichloride; diethylamino-sulfur trifluoride; water; N,N-dimethyl-formamide; sodium hydroxide;
In
methanol; dichloromethane;