1-(4-Aminophenyl)piperidine-4-carboxamide

Base Information

Chemical Name:1-(4-Aminophenyl)piperidine-4-carboxamide
CAS No.:223786-50-3
Molecular Formula:C12H17N3O
Molecular Weight:219.286
Hs Code.:2933399090
European Community (EC) Number:858-435-4
DSSTox Substance ID:DTXSID90588549
Wikidata:Q82481281
Mol file:223786-50-3.mol

Synonyms:1-(4-aminophenyl)piperidine-4-carboxamide;223786-50-3;SCHEMBL77188;F2190-0679;DTXSID90588549;AKOS000147621;MCULE-7030156610;1-(4-aminophenyl)-4-piperidinecarboxamide;DB-131831;EN300-61334;VU0494923-1;G19480;1-(4-Aminophenyl)piperidine-4-carboxamide, AldrichCPR;Z246072566

Suppliers and Price of 1-(4-Aminophenyl)piperidine-4-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(4-aminophenyl)piperidine-4-carboxamide
250mg
$ 265.00

Matrix Scientific
1-(4-Aminophenyl)piperidine-4-carboxamide 95%+
1g
$ 400.00

Matrix Scientific
1-(4-Aminophenyl)piperidine-4-carboxamide 95%+
2.500g
$ 872.00

Matrix Scientific
1-(4-Aminophenyl)piperidine-4-carboxamide 95%+
5g
$ 1318.00

American Custom Chemicals Corporation
1-(4-AMINOPHENYL)PIPERIDINE-4-CARBOXAMIDE 95.00%
5G
$ 1506.05

American Custom Chemicals Corporation
1-(4-AMINOPHENYL)PIPERIDINE-4-CARBOXAMIDE 95.00%
2.5G
$ 1201.49

American Custom Chemicals Corporation
1-(4-AMINOPHENYL)PIPERIDINE-4-CARBOXAMIDE 95.00%
1G
$ 837.99

Total 4 raw suppliers

Chemical Property of 1-(4-Aminophenyl)piperidine-4-carboxamide

Chemical Property:

Boiling Point:505.1±50.0 °C(Predicted)
PKA:16.45±0.20(Predicted)
PSA：73.34000
Density:1.202±0.06 g/cm3(Predicted)
LogP:2.76640
XLogP3:0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:219.137162174
Heavy Atom Count:16
Complexity:241

Purity/Quality:

NLT 98% ^*data from raw suppliers

1-(4-aminophenyl)piperidine-4-carboxamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1C(=O)N)C2=CC=C(C=C2)N

Technology Process of 1-(4-Aminophenyl)piperidine-4-carboxamide

There total 6 articles about 1-(4-Aminophenyl)piperidine-4-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 223786-49-0
1-(4-nitrophenyl)piperidine-4-carboxamide

: 223786-50-3
1-(4-amino-phenyl)-piperidine-4-carboxylic acid amide

Guidance literature:

Reference yield:

: 350-46-9,178603-76-4
4-Fluoronitrobenzene

: 223786-50-3
1-(4-amino-phenyl)-piperidine-4-carboxylic acid amide

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / potassium carbonate / dimethylformamide / 13 h / 90 °C

2: H₂ / Pd/C / ethanol / 16 h / 20 °C

With hydrogen; potassium carbonate; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2004.02.022

Reference yield:

: 39546-32-2
4-carboxamidopiperidine

: 223786-50-3
1-(4-amino-phenyl)-piperidine-4-carboxylic acid amide

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / potassium carbonate / dimethylformamide / 13 h / 90 °C

2: H₂ / Pd/C / ethanol / 16 h / 20 °C

With hydrogen; potassium carbonate; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2004.02.022