5-Hexen-1-one, 1-phenyl-

Base Information

• Chemical Name: 5-Hexen-1-one, 1-phenyl-
• CAS No.: 22524-25-0
• Molecular Formula: C12H14O
• Molecular Weight: 174.243
• Mol file: 22524-25-0.mol

Synonyms:1-phenyl-5-en-1-one;1-phenyl-5-hexene-1-one;5-benzoyl-1-pentene;1-Phenylhex-5-en-1-one;1-phenyl-5-hexen-1-one;

Chemical Property of 5-Hexen-1-one, 1-phenyl-

Chemical Property:

• PSA: 17.07000
• LogP: 3.22560

Purity/Quality:

99% ^*data from raw suppliers

1-Phenylhex-5-en-1-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Hexen-1-one, 1-phenyl-

There total 68 articles about 5-Hexen-1-one, 1-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1-phenylhex-5-en-1-ol (144121-60-8,144121-69-7,65727-70-0) → 1-phenylhex-5-en-1-one (22524-25-0)

Guidance literature:

With pyridinium chlorochromate; In dichloromethane; Inert atmosphere;

DOI:10.1002/anie.201402010

Reference yield: 93.0%

bromopentene (1119-51-3) + benzonitrile (100-47-0) → 1-phenylhex-5-en-1-one (22524-25-0)

Guidance literature:

bromopentene; With iodine; magnesium; In diethyl ether; for 0.25h; Inert atmosphere; Reflux;

benzonitrile; In diethyl ether; at 20 ℃; for 12h; Inert atmosphere;

DOI:10.1002/cmdc.202000801

Reference yield: 91.0%

2-Hydroxy-1,2-diphenyl-hept-6-en-1-one (73172-45-9) → 1-phenylhex-5-en-1-one (22524-25-0) + benzoic acid (65-85-0,8013-63-6)

Guidance literature:

With potassium hydroxide; dihydrogen peroxide;

DOI:10.1055/s-1980-28914

upstream raw materials:

1-phenylcyclohexanol

2-Hydroxy-1,2-diphenyl-hept-6-en-1-one

1-phenyl-3-(tributylstannyl)cyclohexanol

bromopentene

Downstream raw materials:

(R,S)-1-phenyl-2-methylcyclopentanol

1-phenyl-5,6-epoxyhexan-1-one

1-phenylhex-5-en-1-ol

1-(benzenesulfonyl)-2-phenyl-1-(phenylsulfanyl)hept-6-en-2-ol