(2-Ethylphenyl)(phenyl)methanone

Base Information

• Chemical Name: (2-Ethylphenyl)(phenyl)methanone
• CAS No.: 22679-42-1
• Molecular Formula: C15H14O
• Molecular Weight: 210.276
• European Community (EC) Number: 683-769-0
• DSSTox Substance ID: DTXSID70408074
• Nikkaji Number: J1.316.793A
• Wikidata: Q82213438
• Mol file: 22679-42-1.mol

Synonyms:(2-ethylphenyl)(phenyl)methanone;22679-42-1;(2-ethylphenyl)-phenylmethanone;29256-97-1;Methanone, (ethylphenyl)phenyl-;ethyl benzophenone;(2-ETHYL-PHENYL)-PHENYL-METHANONE;SCHEMBL723171;DTXSID70408074;MFCD00229881;AKOS017547728;(2-Ethylphenyl)(phenyl)methanone, 97%;A1-16078

Chemical Property of (2-Ethylphenyl)(phenyl)methanone

Chemical Property:

• Boiling Point: 165 °C(Press: 18 Torr)
• PSA: 17.07000
• Density: 1.049±0.06 g/cm3(Predicted)
• LogP: 3.48000
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 210.104465066
• Heavy Atom Count: 16
• Complexity: 228

Purity/Quality:

98%,99%, ^*data from raw suppliers

(2-ETHYL-PHENYL)-PHENYL-METHANONE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC1=CC=CC=C1C(=O)C2=CC=CC=C2

Technology Process of (2-Ethylphenyl)(phenyl)methanone

There total 33 articles about (2-Ethylphenyl)(phenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

N-benzoyl-N-methyl-4-methylbenzenesulfonamide (10533-83-2) + bis(2-ethylphenyl)borinic acid (1519010-69-5) → 2-ethylbenzophenone (22679-42-1)

Guidance literature:

With [1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](3-chloropyridyl)palladium(ll) dichloride; potassium carbonate; In tetrahydrofuran; at 65 ℃; for 12h; Inert atmosphere; Schlenk technique;

DOI:10.1016/j.tetlet.2018.05.003

Reference yield: 92.0%

bis(2-ethylphenyl)borinic acid (1519010-69-5) + N-(3,5-bis(trifluoromethyl)phenyl)-N-tosylbenzamide → 2-ethylbenzophenone (22679-42-1)

Guidance literature:

With (bis(tricyclohexyl)phosphine)palladium(II) dichloride; potassium carbonate; tricyclohexylphosphine; In 1,4-dioxane; at 110 ℃; for 6h; Inert atmosphere; Schlenk technique;

DOI:10.1016/j.jorganchem.2015.07.009

Reference yield: 84.0%

2-ethylphenyl boronic acid (90002-36-1) + N,N-phenyl-p-toluenesulfonylbenzamide (74542-54-4) → 2-ethylbenzophenone (22679-42-1)

Guidance literature:

With (bis(tricyclohexyl)phosphine)palladium(II) dichloride; potassium carbonate; tricyclohexylphosphine; In 1,4-dioxane; at 110 ℃; for 12h; Inert atmosphere; Schlenk technique;

DOI:10.1039/c5cc00430f

upstream raw materials:

o-ethylbenzonitrile

1,2-bis-(2-ethyl-phenyl)-1,2-diphenyl-ethane-1,2-diol

Phenetole

2-ethylbenzoyl chloride

Downstream raw materials:

4-methyl-2,9-diphenyl-3a,4,9,9a-tetrahydro-4r,9c-epioxido-benzo[f]isoindole-1,3-dione

(+/-)-2-Aethyl-benzhydrylchlorid

2-[2-(benzoyl)phenyl] propanoic acid

Refernces

• 1、 Ammar, Muhammad,Jiang, Sai,Ji, Shengfu. "Heteropoly acid encapsulated into zeolite imidazolate framework (ZIF-67) cage as an efficient heterogeneous catalyst for Friedel-Crafts acylation". . p. 303 - 310. Retrieved 2015/11/17.
• 2、 Tran, Phuong Hoang,Hansen, Poul Erik,Nguyen, Hai Truong,Le, Thach Ngoc. "Erbium trifluoromethanesulfonate catalyzed Friedel-Crafts acylation using aromatic carboxylic acids as acylating agents under monomode-microwave irradiation". . p. 612 - 618. Retrieved 2015/02/19.