2,2'-Diacetyl-9,9'-spirobifluorene

Base Information

• Chemical Name: 2,2'-Diacetyl-9,9'-spirobifluorene
• CAS No.: 22824-83-5
• Molecular Formula: C₂₉H₂₀O₂
• Molecular Weight: 400.477
• DSSTox Substance ID: DTXSID30463588
• Nikkaji Number: J833.149I,J3.416.915B,J3.416.916K
• Wikidata: Q82288540
• Mol file: 22824-83-5.mol

Synonyms:2,2'-diacetyl-9,9'-spirobifluorene;22824-83-5;1-(2'-acetyl-9,9'-spirobi[fluorene]-2-yl)ethanone;1,1'-(9,9'-Spirobi[fluorene]-2,2'-diyl)diethanone;SCHEMBL599077;DTXSID30463588;FVLANAMJWVQMQQ-UHFFFAOYSA-N;(Ethanone, 1,1'-(9,9'-spirobi[9H-fluorene]-2,2'-diyl)bis-);1-(2'-acetyl-9, 9'-spirobi[fluorene]-2-yl)ethanone

Chemical Property of 2,2'-Diacetyl-9,9'-spirobifluorene

Chemical Property:

• PSA: 34.14000
• LogP: 6.43530
• XLogP3: 5.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 400.146329876
• Heavy Atom Count: 31
• Complexity: 677

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)C1=CC2=C(C=C1)C3=CC=CC=C3C24C5=CC=CC=C5C6=C4C=C(C=C6)C(=O)C

Technology Process of 2,2'-Diacetyl-9,9'-spirobifluorene

There total 11 articles about 2,2'-Diacetyl-9,9'-spirobifluorene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

9,9'-spirobifluorene (159-66-0) + acetyl chloride (75-36-5) → 1,1'-(9,9'-spirobi[fluorene]-2,7′-diyl)diethanone (22824-83-5,138257-22-4)

Guidance literature:

With aluminum (III) chloride; In nitromethane; dichloromethane; at 20 ℃; for 12h; Inert atmosphere; Schlenk technique;

DOI:10.1002/ejoc.201402738

Reference yield: 89.0%

9,9'-spirobifluorene (159-66-0) → 1,1'-(9,9'-spirobi[fluorene]-2,7′-diyl)diethanone (22824-83-5,138257-22-4)

Guidance literature:

With aluminum (III) chloride; acetyl chloride; In carbon disulfide; Heating;

DOI:10.3762/bjoc.10.40

Reference yield: 11.0%

9,9'-spirobifluorene (159-66-0) + acetyl chloride (75-36-5) → 1-(9,9'-spirobi[9H-fluoren]-2-yl)ethanone (22824-82-4) + 1,1'-(9,9'-spirobi[fluorene]-2,7′-diyl)diethanone (22824-83-5,138257-22-4)

Guidance literature:

With aluminum (III) chloride; In carbon disulfide; for 1h; Reflux;

DOI:10.3987/COM-09-11666

upstream raw materials:

9,9'-spirobifluorene

acetyl chloride

9-fluorenone

2-Bromobiphenyl

Downstream raw materials:

2,2'-bis(4-amino-2-trifluoromethylphenoxy)-9,9'-spirobifluorene

2,2'-bis(4-nitro-2-trifluoromethylphenoxy)-9,9'-spirobifluorene