(2-((Trimethylsilyl)ethynyl)phenyl)methanol

Base Information

Chemical Name:(2-((Trimethylsilyl)ethynyl)phenyl)methanol
CAS No.:229027-92-3
Molecular Formula:C12H16OSi
Molecular Weight:204.344
Hs Code.:
European Community (EC) Number:630-755-7
Nikkaji Number:J1.252.925B
Mol file:229027-92-3.mol

Synonyms:(2-((Trimethylsilyl)ethynyl)phenyl)methanol;2-(Trimethylsilylethynyl)benzyl alcohol

Suppliers and Price of (2-((Trimethylsilyl)ethynyl)phenyl)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of (2-((Trimethylsilyl)ethynyl)phenyl)methanol

Chemical Property:

Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:204.097041664
Heavy Atom Count:14
Complexity:240

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C[Si](C)(C)C#CC1=CC=CC=C1CO

Technology Process of (2-((Trimethylsilyl)ethynyl)phenyl)methanol

There total 9 articles about (2-((Trimethylsilyl)ethynyl)phenyl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 5159-41-1
2-iodobenzyl alcohol

: 1066-54-2
trimethylsilylacetylene

: 229027-92-3
{2-[2-(trimethylsilyl)ethynyl]phenyl}methanol

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; at 40 ℃; for 5h;
DOI:10.1016/j.tet.2003.04.003

Reference yield: 95.0%

: 77123-58-1
2-[2-(trimethylsilyl)ethynyl]benzaldehyde

: 229027-92-3
{2-[2-(trimethylsilyl)ethynyl]phenyl}methanol

Guidance literature:: With sodium tetrahydroborate; In tetrahydrofuran; methanol; at 0 ℃; for 0.5h;
DOI:10.1021/ol303188u

Reference yield: 89.0%

: 77123-58-1
2-[2-(trimethylsilyl)ethynyl]benzaldehyde

: 77123-57-0
4-[(trimethylsilyl)ethynyl]bezaldehyde

: 229027-92-3
{2-[2-(trimethylsilyl)ethynyl]phenyl}methanol

: 275386-60-2
4-(hydroxymethyl)-1-(trimethylsilylethynyl)benzene

Guidance literature:: 2-[2-(trimethylsilyl)ethynyl]benzaldehyde; 4-[(trimethylsilyl)ethynyl]bezaldehyde; With gallium(III) trichloride; In dichloromethane; at -78 ℃; for 0.5h;

With triphenylstannane; at -78 ℃; for 1h; Further stages.;
DOI:10.1021/ja994000e