1-Methylquinoline-2,3,4(1H)-trione

Base Information

• Chemical Name: 1-Methylquinoline-2,3,4(1H)-trione
• CAS No.: 2291-40-9
• Molecular Formula: C10H7NO3
• Molecular Weight: 189.16700
• Hs Code.: 2933499090
• Mol file: 2291-40-9.mol

Synonyms:1-Methyl-1,2,3,4-tetra-hydroquinoline-2,3,4-trione;N-Methyl-chinisatin;1-Methyl-2,3,4-trioxo-1,2,3,4-tetrahydrochinolin;1-methyl-1H-quinoline-2,3,4-trione;1-Methyl-1H-chinolin-2,3,4-trion;N-Methylquinisatine;2,3,4-Trioxo-1-methyl-1,2,3,4-tetrahydro-chinolin;

Chemical Property of 1-Methylquinoline-2,3,4(1H)-trione

Chemical Property:

• PSA: 54.45000
• LogP: 0.47980
• Storage Temp.: 2-8°C

Purity/Quality:

98.5% ^*data from raw suppliers

1-Methylquinoline-2,3,4(1H)-trione 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Methylquinoline-2,3,4(1H)-trione

There total 8 articles about 1-Methylquinoline-2,3,4(1H)-trione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

4-hydroxy-1-methyl-2(1H)-quinolone (1677-46-9) → 1-Methyl-1,2,3,4-tetra-hydroquinoline-2,3,4-trione (2291-40-9)

Guidance literature:

4-hydroxy-1-methyl-2(1H)-quinolone; With [bis(acetoxy)iodo]benzene; potassium hydroxide; In methanol; at 0 - 20 ℃;

With hydrogenchloride; In tetrahydrofuran; water; at 80 ℃; for 2h;

DOI:10.1080/00304940802711085

Reference yield: 12.0%

4-hydroxy-1-methyl-2(1H)-quinolone (1677-46-9) → 1-Methyl-1,2,3,4-tetra-hydroquinoline-2,3,4-trione (2291-40-9) + N-methyl-3,3-dihydroxyquinoline-2,4-dione (84261-55-2)

Guidance literature:

With rose bengal; In methanol; for 26h; Photolysis;

DOI:10.1080/00304940802711085

Reference yield:

3,3-Dibromo-1-methyl-1H-quinoline-2,4-dione (112254-37-2) → 1-Methyl-1,2,3,4-tetra-hydroquinoline-2,3,4-trione (2291-40-9)

Guidance literature:

With oxygen; methylene blue; In toluene; for 15h; Ambient temperature; Irradiation;

DOI:10.1055/s-1987-27986

upstream raw materials:

1-methyl-1H-quinoline-2,3,4-trione-3-oxime

3,3-Dibromo-1-methyl-1H-quinoline-2,4-dione

ethanol

3,4-Dihydroxy-1-methyl-chinolin-2(1H)-on

Downstream raw materials:

6-Methyl-5-oxo-2,2,2-triphenyl-3,4,5,6-tetrahydro-2H-1,2-oxaphosphorino<5,6-c>quinolinyl-3,4-dicarboxylic acid diethyl ester

1-Methyl-1',3'-diphenyl-2,3-dihydrospiro-2,2',5'-trion

1,1''-Dimethyl-5'(4-tolylimino)dispiro-2(1H),2''(1''H),4,4''-tetron

Refernces

• 1、 Mahran, M. Refat,Abdou, Wafaa M.,Sidky, Mahmoud M.,Wamhoff, Heinrich. "Singel-Oxygen Photolysis of Dihaloketones. A Facile and Efficient Approach to Vicinal Triketones and Their Monohydrates". . p. 506 - 508. Retrieved 2007/10/02.