4-Hydrazinylaniline

Base Information

• Chemical Name: 4-Hydrazinylaniline
• CAS No.: 23197-24-2
• Molecular Formula: C6H9N3
• Molecular Weight: 123.158
• DSSTox Substance ID: DTXSID10524404
• Nikkaji Number: J2.262.974C
• Wikidata: Q82391245
• Mol file: 23197-24-2.mol

Synonyms:4-Hydrazinylaniline;23197-24-2;4-Hydrazinyl-Benzenamine;Benzenamine, 4-hydrazinyl-;Benzenamine, 4-hydrazino-;4-amino-phenylhydrazine;SCHEMBL1709616;DTXSID10524404;AMY20681;AKOS003626434;A905346

Chemical Property of 4-Hydrazinylaniline

Chemical Property:

• XLogP3: 0.9
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 123.079647300
• Heavy Atom Count: 9
• Complexity: 76.4

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1N)NN

Technology Process of 4-Hydrazinylaniline

There total 4 articles about 4-Hydrazinylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4-nitrophenylhydrazone (100-16-3) → 4-hydrazino-aniline (23197-24-2)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol;

DOI:10.1016/j.bmcl.2005.06.006

Reference yield:

acetophenon-(4-amino-phenylhydrazone) → 4-hydrazino-aniline (23197-24-2)

Guidance literature:

With hydrogenchloride; at 0 ℃;

Reference yield:

acetophenone p-nitrophenylhydrazone (2675-22-1,41902-83-4) → 4-hydrazino-aniline (23197-24-2)

Guidance literature:

Multi-step reaction with 2 steps

1: Na₂S₂O₄; alcoholic ammonia

2: hydrochloric acid / 0 °C

With hydrogenchloride; sodium dithionite; ammonia;

upstream raw materials:

4-nitrophenylhydrazone

acetophenone p-nitrophenylhydrazone

Downstream raw materials:

4-phenylalanine

p-aminoantipyrine

2-(4-amino-phenyl)-5-methyl-1,2-dihydro-pyrazol-3-one

Refernces

• 1、 Elhampour, Ali,Heravi, Majid M.,Nemati, Firouzeh,Piri, Mohadese. "Silver nanoparticles supported on P, Se-codoped g-C3N4 nanosheet as a novel heterogeneous catalyst for reduction of nitroaromatics to their corresponding amines". . . Retrieved 2021/06/21.
• 2、 ?ak?r, Sinem,Türkmen, Hayati. "Synthesis of water soluble Pd-Piperidoimidazolin-2-ylidene complexes and their catalytic activities in neat water". . . Retrieved 2020/02/04.