Technology Process of 2H-Pyran-2-one,
tetrahydro-6-[(3Z,6Z,9Z,12Z)-1-iodo-3,6,9,12-pentadecatetraenyl]-
There total 1 articles about 2H-Pyran-2-one,
tetrahydro-6-[(3Z,6Z,9Z,12Z)-1-iodo-3,6,9,12-pentadecatetraenyl]- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
fish oil fatty acids; mixture of;
With
potassium hydrogencarbonate;
In
ethanol; water;
With
iodine;
In
ethanol; hexane; water;
at 24 ℃;
for 16h;
- Guidance literature:
-
With
water; potassium hydroxide;
In
methanol;
at 60 ℃;
for 4h;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 8 steps
1.1: potassium hydroxide / methanol; water / 4 h / 0 - 60 °C / Inert atmosphere
2.1: sodium periodate / tetrahydrofuran; water / 1 h / 0 °C / Inert atmosphere
3.1: sodium tetrahydroborate / methanol / 0.5 h / 0 °C
4.1: bis(acetylacetonate)oxovanadium; tert.-butylhydroperoxide / toluene / 0.08 h / 0 - 20 °C
5.1: perchloric acid / 1,2-dimethoxyethane; water / 0 - 20 °C / Inert atmosphere
6.1: sodium periodate / tetrahydrofuran; water / 0 °C / Inert atmosphere
7.1: diethylzinc / 1,2-dimethoxyethane / 24 h / -78 - -4 °C / Inert atmosphere; Darkness
7.2: -25 °C / Darkness; Inert atmosphere
8.1: pyridine / 1 h / 20 °C
With
tert.-butylhydroperoxide; sodium tetrahydroborate; sodium periodate; perchloric acid; bis(acetylacetonate)oxovanadium; diethylzinc; potassium hydroxide;
In
tetrahydrofuran; pyridine; methanol; 1,2-dimethoxyethane; water; toluene;
DOI:10.1039/c4ob02324b
![5-[(3Z,6Z,9Z,12Z,15Z)-1-iodooctadeca-3,6,9,12,15-pentaenyl]dihydro-2(3H)-furanone](/Databaselist/images/loading.webp)
