N-(2-chloroethyl)formamide

Base Information

• Chemical Name: N-(2-chloroethyl)formamide
• CAS No.: 24589-68-2
• Molecular Formula: C3H6 Cl N O
• Molecular Weight: 107.54
• Mol file: 24589-68-2.mol

Synonyms:N-(2-Chloroethyl)formamide;N-(b-Chloroethyl)formamide; NSC 68741

Chemical Property of N-(2-chloroethyl)formamide

Chemical Property:

• Vapor Pressure: 0.00389mmHg at 25°C
• Boiling Point: 280°Cat760mmHg
• Flash Point: 123.1°C
• Density: 1.125g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(2-chloroethyl)formamide

There total 3 articles about N-(2-chloroethyl)formamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

2-chloroethanamine hydrochloride (870-24-6) + formic acid ethyl ester (109-94-4) → N-(2-chloroethyl)formamide (24589-68-2)

Guidance literature:

With sodium carbonate; In ethanol; for 20h; Ambient temperature;

DOI:10.1021/jm00156a024

Reference yield:

(2-hydroxyethyl)-formamide (693-06-1) → N-(2-chloroethyl)formamide (24589-68-2)

Guidance literature:

With thionyl chloride; zuletzt in der Waerme;

DOI:10.1021/ja01276a036 DOI:10.1021/jo01157a024

Reference yield:

→ (-)-2-[2-(N-formyl)aminoethylthio]-3-carboethoxy-5-carbomethoxy-4-(3-nitrophenyl)-6-methyl-1,4-dihydropyridine + N-(2-chloroethyl)formamide (24589-68-2)

Guidance literature:

upstream raw materials:

(2-hydroxyethyl)-formamide

2-chloroethanamine hydrochloride

formic acid ethyl ester

Downstream raw materials:

4,5-dihydro-1,3-oxazol