p-Methoxyphenyldimethylchlorosilane

Base Information

• Chemical Name: p-Methoxyphenyldimethylchlorosilane
• CAS No.: 2372-33-0
• Molecular Formula: C9H13ClOSi
• Molecular Weight: 200.74
• DSSTox Substance ID: DTXSID40448407
• Nikkaji Number: J46.913K
• Wikidata: Q63399404
• Mol file: 2372-33-0.mol

Synonyms:2372-33-0;p-methoxyphenyldimethylchlorosilane;Silane, chloro(4-methoxyphenyl)dimethyl-;chloro-(4-methoxyphenyl)-dimethylsilane;SCHEMBL1200237;DTXSID40448407;RTYNSTRFACIKRL-UHFFFAOYSA-N;4-methoxyphenyldimethyl-chlorosilane;PARA-METHOXYPHENYLDIMETHYLCHLOROSILANE;CHLORO(4-METHOXYPHENYL)DIMETHYLSILANE;Q63399404

Chemical Property of p-Methoxyphenyldimethylchlorosilane

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 200.0424193
• Heavy Atom Count: 12
• Complexity: 142

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)[Si](C)(C)Cl

Technology Process of p-Methoxyphenyldimethylchlorosilane

There total 9 articles about p-Methoxyphenyldimethylchlorosilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

1-bromo-4-methoxy-benzene (104-92-7) + dimethylsilicon dichloride (75-78-5,30107-43-8) → chlorodimethyl(4-methoxyphenyl)silane (2372-33-0)

Guidance literature:

[2,2]bipyridinyl; (2,2'-bipyridine)nickel(II) dibromide; In tetrahydrofuran; Product distribution / selectivity; Electrolysis;

Reference yield: 82.0%

→ chlorodimethyl(4-methoxyphenyl)silane (2372-33-0) + di(4-methoxy-phenyl)-dimethyl-silane (69983-36-4)

Guidance literature:

With bis(tricyclohexylphosphine)nickel(II) dichloride; triethylaluminum; dimethylaluminum chloride; In 1,4-dioxane; hexane; 1,3,5-trimethyl-benzene; at 90 ℃; for 0.5h;

In hexane; toluene; 1,3,5-trimethyl-benzene; at 90 ℃; for 24h;

Reference yield: 61.0%

(p-methoxyphenyl)dimethylsilane (1432-38-8) → chlorodimethyl(4-methoxyphenyl)silane (2372-33-0)

Guidance literature:

With tetrachloromethane; palladium dichloride; at 80 ℃; for 24h;

DOI:10.1016/j.tetlet.2017.10.008

upstream raw materials:

1-bromo-4-methoxy-benzene

dimethylsilicon dichloride

1,2-dichlorotetramethylsilane

4-methoxy-benzoyl chloride

Downstream raw materials:

N-(p-Methoxyphenyldimethylsilyl)-acetamid

1,2-di-p-methoxyphenyl-1,1,2,2-tetramethyldisilane

1,3-bis(4′-methoxyphenyl)-1,1,3,3-tetramethyldisiloxane

(p-Methoxy-phenyl)-dimethyl-fluorsilan