3-Methyl-5-phenylthiophene-2-carboxylic acid

Base Information

Chemical Name:3-Methyl-5-phenylthiophene-2-carboxylic acid
CAS No.:23806-25-9
Molecular Formula:C12H10O2S
Molecular Weight:218.276
Hs Code.:
European Community (EC) Number:886-086-8
DSSTox Substance ID:DTXSID20556054
Wikidata:Q82437524
Mol file:23806-25-9.mol

Synonyms:3-methyl-5-phenylthiophene-2-carboxylic acid;23806-25-9;2-Thiophenecarboxylic acid, 3-methyl-5-phenyl-;SCHEMBL3585269;DTXSID20556054;HKLGQHBZEAPLDC-UHFFFAOYSA-N;3-methyl-5-phenyl-2-thiophenecarboxylic acid;3-Methyl-5-phenyl-thiophene-2-carboxylic acid;EN300-9429278

Suppliers and Price of 3-Methyl-5-phenylthiophene-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of 3-Methyl-5-phenylthiophene-2-carboxylic acid

Chemical Property:

PSA：65.54000
LogP:3.42170
XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:218.04015073
Heavy Atom Count:15
Complexity:236

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(SC(=C1)C2=CC=CC=C2)C(=O)O

Technology Process of 3-Methyl-5-phenylthiophene-2-carboxylic acid

There total 7 articles about 3-Methyl-5-phenylthiophene-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 513-35-9
2-methyl-but-2-ene

: 160417-30-1
3-methyl-5-phenylthiophene-2-carbaldehyde

petrol: petrol

: 23806-25-9
3-methyl-5-phenylthiophene-2-carboxylic acid

Guidance literature:: With sodium dihydrogenphosphate; NaClO₂; In N-methyl-acetamide; water; ethyl acetate;

Reference yield: 53.0%

: 595565-66-5
(2Z,4E)-2-Mercapto-3-methyl-5-phenyl-penta-2,4-dienoic acid

: 23806-25-9
3-methyl-5-phenylthiophene-2-carboxylic acid

Guidance literature:: With iodine; In 1,2-dimethoxyethane; for 240h; Ambient temperature;

Reference yield:

: 14300-29-9
3-Methyl-2-phenylthiophene

: 23806-25-9
3-methyl-5-phenylthiophene-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / N-bromosuccinimide / 2,2'-azobisisobutyronitrile / CCl₄ / 1 h / Heating

2: 1. Mg; / 1. ether, reflux, 3h; 2. ether

With N-Bromosuccinimide; magnesium; 2,2'-azobis(isobutyronitrile); In tetrachloromethane;