4,4,4-Trifluoro-1-(4-methylphenyl)-3-(trifluoromethyl)but-2-en-1-one

Base Information

Chemical Name:4,4,4-Trifluoro-1-(4-methylphenyl)-3-(trifluoromethyl)but-2-en-1-one
CAS No.:35443-92-6
Molecular Formula:C12H8 F6 O
Molecular Weight:282.1817
Hs Code.:
NSC Number:160229
DSSTox Substance ID:DTXSID50303694
Mol file:35443-92-6.mol

Synonyms:35443-92-6;4,4,4-trifluoro-1-(4-methylphenyl)-3-(trifluoromethyl)but-2-en-1-one;NSC160229;DTXSID50303694;NSC-160229;2-Buten-1-one, 4,4,4-trifluoro-1-(4-methylphenyl)-3-(trifluoromethyl)-

Suppliers and Price of 4,4,4-Trifluoro-1-(4-methylphenyl)-3-(trifluoromethyl)but-2-en-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4,4,4-Trifluoro-1-(4-methylphenyl)-3-(trifluoromethyl)but-2-en-1-one

Chemical Property:

Vapor Pressure:0.00113mmHg at 25°C
Boiling Point:300.3°C at 760 mmHg
Flash Point:115.1°C
Density:1.325g/cm³
XLogP3:4.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:2
Exact Mass:282.04793385
Heavy Atom Count:19
Complexity:341

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C(=O)C=C(C(F)(F)F)C(F)(F)F

Technology Process of 4,4,4-Trifluoro-1-(4-methylphenyl)-3-(trifluoromethyl)but-2-en-1-one

There total 4 articles about 4,4,4-Trifluoro-1-(4-methylphenyl)-3-(trifluoromethyl)but-2-en-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 143211-30-7
4,4,4-Trifluoro-3-hydroxy-1-p-tolyl-3-trifluoromethyl-butan-1-one

: 35443-92-6
4,4,4-Trifluoro-1-p-tolyl-3-trifluoromethyl-but-2-en-1-one

Guidance literature:: With pyridine; trifluoroacetic anhydride; In diethyl ether; at 0 ℃; for 1h;
DOI:10.1002/prac.19923340304

Reference yield:

: 54731-27-0
1-p-methylphenyl-1-trimethylsiloxyethene

: 35443-92-6
4,4,4-Trifluoro-1-p-tolyl-3-trifluoromethyl-but-2-en-1-one

Guidance literature:: Multi-step reaction with 3 steps

1: 96 percent / CH₂Cl₂

2: 97 percent / aq. HCl / methanol / 4 h / Ambient temperature

3: 79 percent / (CF₃CO)2O, pyridin / diethyl ether / 1 h / 0 °C

With pyridine; hydrogenchloride; trifluoroacetic anhydride; In methanol; diethyl ether; dichloromethane;
DOI:10.1002/prac.19923340304

Reference yield:

: 143211-23-8
4,4,4-Trifluoro-1-p-tolyl-3-trifluoromethyl-3-trimethylsilanyloxy-butan-1-one

: 35443-92-6
4,4,4-Trifluoro-1-p-tolyl-3-trifluoromethyl-but-2-en-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / aq. HCl / methanol / 4 h / Ambient temperature

2: 79 percent / (CF₃CO)2O, pyridin / diethyl ether / 1 h / 0 °C

With pyridine; hydrogenchloride; trifluoroacetic anhydride; In methanol; diethyl ether;
DOI:10.1002/prac.19923340304