Benzoic acid, 4-(hydroxyamino)-, ethyl ester

Base Information

• Chemical Name: Benzoic acid, 4-(hydroxyamino)-, ethyl ester
• CAS No.: 24171-85-5
• Molecular Formula: C9H11NO3
• Molecular Weight: 181.191
• Mol file: 24171-85-5.mol

Synonyms:4-hydroxyamino-benzoic acid ethylester;Benzoic acid,4-(hydroxyamino)-,ethyl ester;(4-carbethoxyphenyl)hydroxylamine;p-hydroxyaminobenzoic acid etyl ester;4-CO2EtC6H4-NHOH;ethyl 4-(hydroxylamino)benzoate;ethyl p-(hydroxylamino)benzoate;

Chemical Property of Benzoic acid, 4-(hydroxyamino)-, ethyl ester

Chemical Property:

• PSA: 58.56000
• LogP: 1.73740

Purity/Quality:

97% ^*data from raw suppliers

Ethyl4-(hydroxyamino)benzoate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzoic acid, 4-(hydroxyamino)-, ethyl ester

There total 6 articles about Benzoic acid, 4-(hydroxyamino)-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

ethyl 4-nitrobenzoate (99-77-4) → ethyl 4-(hydroxylamino)benzoate (24171-85-5)

Guidance literature:

With ammonium chloride; zinc; In acetone; at 15 - 20 ℃; for 0.0833333h; Irradiation;

DOI:10.1016/j.tetlet.2005.06.126

Reference yield: 95.0%

4-CO2EtC6H4-N(Teoc)OTBS (1303610-40-3) → ethyl 4-(hydroxylamino)benzoate (24171-85-5)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 40 ℃; for 1.5h; Inert atmosphere;

DOI:10.1016/j.tetlet.2010.12.034

Reference yield: 2.0%

ethyl 4-nitrobenzoate (99-77-4) → ethyl 4-(hydroxylamino)benzoate (24171-85-5) + p-aminoethylbenzoate (94-09-7)

Guidance literature:

With sodium tetrahydroborate; sodium selenite; In water; at 37 ℃; for 1h;

DOI:10.1016/S0040-4039(00)91647-2

upstream raw materials:

ethyl 4-nitrobenzoate

p-aminoethylbenzoate

4-CO₂EtC₆H₄-N(Teoc)OTBS

Downstream raw materials:

α-<2-(2-furyl)ethenyl>-N-(4-carbethoxyphenyl)nitrone

α-(4-methoxyphenyl)-N-(4-carbethoxyphenyl)nitrone

α-(4-(diethylamino)phenyl)-N-(4-carbethoxyphenyl)nitrone

α-styryl-N-(4-carbethoxyphenyl)nitrone