9H-Carbazole-3-carboxaldehyde, 6-bromo-9-ethyl-

Base Information

• Chemical Name: 9H-Carbazole-3-carboxaldehyde, 6-bromo-9-ethyl-
• CAS No.: 24301-72-2
• Molecular Formula: C15H12BrNO
• Molecular Weight: 302.17
• DSSTox Substance ID: DTXSID40462067
• Nikkaji Number: J2.076.974B
• Wikidata: Q82286538
• Mol file: 24301-72-2.mol

Synonyms:24301-72-2;6-bromo-9-ethyl-9H-carbazole-3-carbaldehyde;6-BROMO-9-ETHYLCARBAZOLE-3-CARBALDEHYDE;9H-Carbazole-3-carboxaldehyde, 6-bromo-9-ethyl-;SCHEMBL16066019;DTXSID40462067;3-bromo-9-ethylcarbazole-6-carboxaldehyde

Chemical Property of 9H-Carbazole-3-carboxaldehyde, 6-bromo-9-ethyl-

Chemical Property:

• PSA: 22.00000
• LogP: 4.38940
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 301.01023
• Heavy Atom Count: 18
• Complexity: 322

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN1C2=C(C=C(C=C2)C=O)C3=C1C=CC(=C3)Br

Technology Process of 9H-Carbazole-3-carboxaldehyde, 6-bromo-9-ethyl-

There total 6 articles about 9H-Carbazole-3-carboxaldehyde, 6-bromo-9-ethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

N-ethyl-3-carbazolealdehyde (7570-45-8) → 6-bromo-9-ethyl-9H-carbazole-3-carbaldehyde (24301-72-2)

Guidance literature:

With N-Bromosuccinimide; In chloroform; acetic acid; at 20 ℃; for 15h; Inert atmosphere;

DOI:10.1016/j.jallcom.2021.161795

Reference yield: 87.0%

3-bromo-9-ethyl-9H-carbazole (57102-97-3) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 6-bromo-9-ethyl-9H-carbazole-3-carbaldehyde (24301-72-2)

Guidance literature:

With trichlorophosphate; for 0.03h; microwave irradiation;

DOI:10.1081/SCC-120038488

Reference yield:

N-ethylcarbazole (86-28-2) → 6-bromo-9-ethyl-9H-carbazole-3-carbaldehyde (24301-72-2)

Guidance literature:

Multi-step reaction with 2 steps

1: POCl₃ / 16 h / 80 °C

2: NBS / dimethylformamide / 16 h / 20 °C

With N-Bromosuccinimide; trichlorophosphate; In N,N-dimethyl-formamide; 1: Vilsmeier-Haack reaction;

DOI:10.1016/j.tet.2006.06.067

upstream raw materials:

N-ethyl-3-carbazolealdehyde

3-bromo-9-ethyl-9H-carbazole

N,N-dimethyl-formamide

N-ethylcarbazole

Downstream raw materials:

6-(2'-(para-pyridyl)ethenyl)-9-ethyl-carbazole-3-aldehyde

C₂₅H₂₈BrN₂O₃P

C₂₅H₂₈BrN₂O₄P

C₂₅H₂₇BrN₃O₅P