2-Methylthiopropionic acid S-ethyl ester

Base Information

• Chemical Name: 2-Methylthiopropionic acid S-ethyl ester
• CAS No.: 2432-50-0
• Molecular Formula: C6H12OS
• Molecular Weight: 132.227
• Hs Code.: 2930909090
• Mol file: 2432-50-0.mol

Synonyms:thioisobutyric acid S-ethyl ester;2-methyl-propanethioic acid;ethyl 2-methylthiopropionate;S-ethyl ester;

Chemical Property of 2-Methylthiopropionic acid S-ethyl ester

Chemical Property:

• PSA: 42.37000
• LogP: 1.92210

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Methylthiopropionic acid S-ethyl ester

There total 3 articles about 2-Methylthiopropionic acid S-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methyl-1,3-oxathiolane (17642-74-9) → ethyl thioacetate (625-60-5) + ethyl β-methylthiopropionate (2432-50-0)

Guidance literature:

With 2-isopropyl-1,3-oxathiolane; di-tert-butyl peroxide; In chlorobenzene; at 130 ℃; under 750.06 Torr; Rate constant; var. pressure (250, 500, 750 MPa);

Reference yield:

2-isopropyl-1,3-oxathiolane (17643-70-8) → ethyl thioacetate (625-60-5) + ethyl β-methylthiopropionate (2432-50-0)

Guidance literature:

With 2-methyl-1,3-oxathiolane; di-tert-butyl peroxide; In chlorobenzene; at 130 ℃; under 750.06 Torr; Rate constant; var. pressure (250, 500, 750 MPa);

Reference yield:

1-bromo-2-<(ethylthio)carbonyl>propane (70166-15-3) → ethylthioacetic acid ethyl ester (20807-99-2) + S-ethyl 2-methylprop-2-enethioate (54667-15-1) + ethyl β-methylthiopropionate (2432-50-0)

Guidance literature:

With tetrabutyl ammonium fluoride; 1ester>ClO4; In N,N-dimethyl-formamide; at 20 ℃; for 3h; Product distribution; electrolysis with Pt electrodes, various time, potential, and CH₃COOH additive;

DOI:10.1246/bcsj.60.311

upstream raw materials:

2-methyl-1,3-oxathiolane

2-isopropyl-1,3-oxathiolane

1-bromo-2-<(ethylthio)carbonyl>propane

Downstream raw materials:

1-methyl-3-phenylpropyl 2-methylpropionate

4-methyl-1-phenylpent-1-yn-3-one

(S)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (E)-(1S,2S)-4-[(2S,4S,6R)-4-(tert-butyl-diphenyl-silanyloxy)-6-ethoxycarbonylmethyl-6-methoxy-tetrahydro-pyran-2-yl]-1-(1-ethylsulfanylcarbonyl-1-methyl-ethyl)-2-methyl-pent-3-enyl ester

(R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (E)-(1S,2S)-4-[(2S,4S,6R)-4-(tert-butyl-diphenyl-silanyloxy)-6-ethoxycarbonylmethyl-6-methoxy-tetrahydro-pyran-2-yl]-1-(1-ethylsulfanylcarbonyl-1-methyl-ethyl)-2-methyl-pent-3-enyl ester