2-(Butylthio)phenol

Base Information

• Chemical Name: 2-(Butylthio)phenol
• CAS No.: 24362-87-6
• Molecular Formula: C10H14OS
• Molecular Weight: 182.287
• Hs Code.: 2930909090
• Mol file: 24362-87-6.mol

Synonyms:2-Butylmercapto-phenol;Phenol,2-(butylthio);o-Hydroxyphenyl-butylsulfid;Monothiobrenzcatechin-S-butylaether;2-butylsulfanyl-phenol;Butyl-(2-hydroxy-phenyl)-sulfid;o-(n-butylthio)phenol;2-Hydroxy-1-butylmercapto-benzol;Phenol,o-(butylthio);

Chemical Property of 2-(Butylthio)phenol

Chemical Property:

• Boiling Point: 270.0±23.0 °C(Predicted)
• PKA: 9.29±0.35(Predicted)
• PSA: 45.53000
• Density: 1.09±0.1 g/cm3(Predicted)
• LogP: 3.28440

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(Butylthio)phenol

There total 7 articles about 2-(Butylthio)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2-(Butylthio)cyclohexanon (37456-99-8) → o-(n-butylthio)phenol (24362-87-6)

Guidance literature:

With bromine; In chloroform; Ambient temperature;

DOI:10.1016/0040-4039(94)85328-2

Reference yield:

ortho-phenitidine (94-70-2) → o-(n-butylthio)phenol (24362-87-6)

Guidance literature:

With hydrogenchloride; at 70 - 90 ℃; Diazotization_.Erwaermen des Reaktionsprodukts mit wss. HBr und Essigsaeure auf 75-85grad und Kochen des erhaltenen Oels mit wss.-aethanol. NaOH;

DOI:10.1021/ja01330a061

Reference yield:

1-bromo-butane (109-65-9) + ortho-mercaptophenol (1121-24-0) → o-(n-butylthio)phenol (24362-87-6)

Guidance literature:

With methanol; sodium hydroxide;

DOI:10.1021/ja01330a061

upstream raw materials:

1-bromo-butane

ortho-mercaptophenol

2-(Butylthio)cyclohexanon

n-Butyl chloride

Downstream raw materials:

Butyl-o-hydroxyphenylsulfon

Butyl-o-hydroxyphenyl-sulfoxid

ortho-mercaptophenol

Refernces

• 1、 Wang, Haolong,Wan, Boshun. "Cu-Catalyzed Coupling of Aryl Iodides with Thiols Using Carbonyl-Phosphine Oxide Ligands". . p. 1129 - 1132. Retrieved 2016/04/19.
• 2、 Samoshin, Vyacheslav V.,Kudryavtsev, Konstantin V.. "Novel reaction: Brominative aromatization of 2-alkyl(aryl)thio cyclohexanones". . p. 7413 - 7414. Retrieved 2007/10/02.