METHYL 4-(4-AMINOPHENOXY)BENZOATE

Base Information

• Chemical Name: METHYL 4-(4-AMINOPHENOXY)BENZOATE
• CAS No.: 24477-92-7
• Molecular Formula: C14H13NO3
• Molecular Weight: 243.25800
• Hs Code.: 2922509090
• Mol file: 24477-92-7.mol

Synonyms:4-Methoxycarbonyl-4'-amino-diphenyloxid;

Chemical Property of METHYL 4-(4-AMINOPHENOXY)BENZOATE

Chemical Property:

• PSA: 61.55000
• LogP: 3.42890

Purity/Quality:

98%min ^*data from raw suppliers

Methyl4-(4-aminophenoxy)benzoate ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of METHYL 4-(4-AMINOPHENOXY)BENZOATE

There total 6 articles about METHYL 4-(4-AMINOPHENOXY)BENZOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

→ methyl 4-(4-{(Z)-[(2-oxo-2,3-dihydro-1H-pyrrolo[3,2-f]quinolin-1-ylidene)methyl]amino}phenoxy)benzoate (297756-93-5) + 4-(4-amino-phenoxy)-benzoic acid methyl ester (24477-92-7)

Guidance literature:

Reference yield: 35.0%

→ methyl 4-(4-{[((Z)-7-oxo-6,7-dihydro-8H-[1,3]thiazolo[5,4-e]indol-8-ylidene)methyl]amino}phenoxy)benzoate (297756-84-4) + 4-(4-amino-phenoxy)-benzoic acid methyl ester (24477-92-7)

Guidance literature:

Reference yield:

methyl 4-(4-nitrophenoxy)benzoate (21120-78-5) → 4-(4-amino-phenoxy)-benzoic acid methyl ester (24477-92-7)

Guidance literature:

With palladium on activated charcoal; Hydrogenation;

upstream raw materials:

methyl 4-(4-nitrophenoxy)benzoate

methyl 4-hydroxylbenzoate

4-Fluoronitrobenzene

Downstream raw materials:

4-[4-((R)-2-tert-Butoxycarbonylamino-3-tritylsulfanyl-propionylamino)-phenoxy]-benzoic acid methyl ester

4-[4-((R)-2-tert-Butoxycarbonylamino-3-tritylsulfanyl-propylamino)-phenoxy]-benzoic acid

4-[4-((R)-2-tert-Butoxycarbonylamino-3-tritylsulfanyl-propionylamino)-phenoxy]-benzoic acid

methyl 4-(4-{(Z)-[(2-oxo-2,3-dihydro-1H-pyrrolo[3,2-f]quinolin-1-ylidene)methyl]amino}phenoxy)benzoate

Refernces

• 1、 -. "Substituted oxidole derivatives as protein tyrosine and as protein serine/threonine kinase inhibitors". . . Retrieved 2008/06/13.