4-Formyl-2-methoxyphenyl 4-methylbenzenesulfonate

Base Information

• Chemical Name: 4-Formyl-2-methoxyphenyl 4-methylbenzenesulfonate
• CAS No.: 246224-09-9
• Molecular Formula: C15H14O5S
• Molecular Weight: 306.339
• DSSTox Substance ID: DTXSID50365818
• Nikkaji Number: J1.225.799F
• Wikidata: Q82150791
• Mol file: 246224-09-9.mol

Synonyms:246224-09-9;4-formyl-2-methoxyphenyl 4-methylbenzenesulfonate;(4-formyl-2-methoxyphenyl) 4-methylbenzenesulfonate;Toluene-4-sulfonic acid 4-formyl-2-methoxy-phenyl ester;4-formyl-2-methoxyphenyl 4-methylbenzenesulphonate;4-formyl-2-methoxyphenyl 4-methylbenzene-1-sulfonate;Benzaldehyde, 3-methoxy-4-[[(4-methylphenyl)sulfonyl]oxy]-;SCHEMBL1936658;3-Methoxy-4-tosyloxybenzaldehyde;DTXSID50365818;HEVNIQOBWMMUIH-UHFFFAOYSA-N;3-Methoxy-4-(tosyloxy)benzaldehyde;BBL023193;MFCD01935657;STL357577;AKOS000295095;UPCMLD0ENAT5293554:001;VS-07348;CS-0219973;EN300-05457;4-formyl-2-methoxyphenyl4-methylbenzenesulfonate;J-015597;Z45511162

Chemical Property of 4-Formyl-2-methoxyphenyl 4-methylbenzenesulfonate

Chemical Property:

• XLogP3: 2.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 5
• Exact Mass: 306.05619472
• Heavy Atom Count: 21
• Complexity: 434

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)OC2=C(C=C(C=C2)C=O)OC

Technology Process of 4-Formyl-2-methoxyphenyl 4-methylbenzenesulfonate

There total 4 articles about 4-Formyl-2-methoxyphenyl 4-methylbenzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

vanillin (121-33-5,8014-42-4) + p-toluenesulfonyl chloride (98-59-9) → 4-formyl-2-methoxyphenyl-1-(4-methylbenzenesulfonate) (246224-09-9)

Guidance literature:

vanillin; With potassium carbonate; In acetone; at 20 ℃; for 0.166667h;

p-toluenesulfonyl chloride; In acetone; for 24h; Heating;

DOI:10.1021/ol048802c

Reference yield: 91.0%

toluene-4-sulfonic acid 4-[1,3]dithian-2-yl-2-methoxy-phenyl ester → 4-formyl-2-methoxyphenyl-1-(4-methylbenzenesulfonate) (246224-09-9)

Guidance literature:

With o-iodoxybenzoic acid monohydrate; In dimethyl sulfoxide; at 20 ℃; for 0.5h;

DOI:10.1016/S0040-4039(02)01346-1

Reference yield:

methyl bromide (74-83-9) → 4-formyl-2-methoxyphenyl-1-(4-methylbenzenesulfonate) (246224-09-9)

Guidance literature:

With ethanol;

upstream raw materials:

methyl bromide

vanillin

p-toluenesulfonyl chloride

Downstream raw materials:

2-methoxy-[1,1'-biphenyl]-4-carbaldehyde

bis(3-methoxy-4-tosylhydroxybenzyl)ether

2-methoxy-4-(2,2,2-trichloro-1-hydroxyethyl)phenyl 4-methylbenzenesulfonate

(S,E)-1-chloro-4-(3-methoxy-4-tosyloxyphenyl)-3-buten-2-yl acetate