5-amino-2-(4-methoxyphenyl)-2,4-dihydro-3H-pyrazol-3-one

Base Information

Chemical Name:5-amino-2-(4-methoxyphenyl)-2,4-dihydro-3H-pyrazol-3-one
CAS No.:24630-93-1
Molecular Formula:C10H11N3O2
Molecular Weight:205.216
Hs Code.:
DSSTox Substance ID:DTXSID70521272
Wikidata:Q82385660
Mol file:24630-93-1.mol

Synonyms:24630-93-1;3-amino-1-(4-methoxyphenyl)-1H-pyrazol-5(4H)-one;3H-Pyrazol-3-one, 5-amino-2,4-dihydro-2-(4-methoxyphenyl)-;5-amino-2-(4-methoxyphenyl)-2,4-dihydro-3H-pyrazol-3-one;DTXSID70521272;AKOS002316020

Suppliers and Price of 5-amino-2-(4-methoxyphenyl)-2,4-dihydro-3H-pyrazol-3-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 5-amino-2-(4-methoxyphenyl)-2,4-dihydro-3H-pyrazol-3-one

Chemical Property:

XLogP3:0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:205.085126602
Heavy Atom Count:15
Complexity:282

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)N2C(=O)CC(=N2)N

Technology Process of 5-amino-2-(4-methoxyphenyl)-2,4-dihydro-3H-pyrazol-3-one

There total 3 articles about 5-amino-2-(4-methoxyphenyl)-2,4-dihydro-3H-pyrazol-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

: 86988-57-0
3-[(4-Methoxy-phenyl)-hydrazono]-3-nitro-propionic acid ethyl ester

: 24630-93-1
5-amino-2-(4-methoxy-phenyl)-1,2-dihydro-pyrazol-3-one

Guidance literature:: With hydrogen; nickel; In methanol; at 40 ℃; for 6h; under 2068.6 Torr;

Reference yield:

: 104-94-9
4-methoxy-aniline

: 24630-93-1
5-amino-2-(4-methoxy-phenyl)-1,2-dihydro-pyrazol-3-one

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) conc. HCl, sodium nitrite; 2.) sodium ethoxide / 1.) water, 0-5 deg C; 2.) ethanol, 5-10 deg C

2: 43 percent / hydrogen / Raney nickel / methanol / 6 h / 40 °C / 2068.6 Torr

With hydrogenchloride; hydrogen; sodium ethanolate; sodium nitrite; nickel; In methanol;