2,1-Benzisothiazole, 1,3-dihydro-1-methyl-, 2,2-dioxide

Base Information

Chemical Name:2,1-Benzisothiazole, 1,3-dihydro-1-methyl-, 2,2-dioxide
CAS No.:24827-66-5
Molecular Formula:C8H9NO2S
Molecular Weight:183.22800
Hs Code.:
DSSTox Substance ID:DTXSID00505005
Nikkaji Number:J722.795G
Wikidata:Q82359824
Mol file:24827-66-5.mol

Synonyms:24827-66-5;2,1-Benzisothiazole, 1,3-dihydro-1-methyl-, 2,2-dioxide;1-methyl-3H-2,1-benzothiazole 2,2-dioxide;SCHEMBL3319807;AMY1909;DTXSID00505005;YRSIGGJLDCPKJN-UHFFFAOYSA-N;1-methyl-2,1-benzothiazoline 2,2-dioxide;1-methyl-1,3-dihydrobenzo[c]isothiazole 2,2-dioxide;1-Methyl-1,3-dihydrobenzo[c]isothiazole-2,2-dioxide;1-Methyl-1,3-dihydro-2,1-benzisothiazole 2,2-dioxide;1-methyl-1,3-dihydro-2|E?,1-benzothiazole-2,2-dione;1-Methyl-1,3-dihydro-2H-2lambda~6~,1-benzothiazole-2,2-dione

Suppliers and Price of 2,1-Benzisothiazole, 1,3-dihydro-1-methyl-, 2,2-dioxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of 2,1-Benzisothiazole, 1,3-dihydro-1-methyl-, 2,2-dioxide

Chemical Property:

PSA：45.76000
LogP:2.11200
XLogP3:0.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:183.03539970
Heavy Atom Count:12
Complexity:267

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C2=CC=CC=C2CS1(=O)=O

Technology Process of 2,1-Benzisothiazole, 1,3-dihydro-1-methyl-, 2,2-dioxide

There total 9 articles about 2,1-Benzisothiazole, 1,3-dihydro-1-methyl-, 2,2-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 111248-89-6
1,3-dihydro-2,1-benzisothiazole 2,2-dioxide

: 74-88-4
methyl iodide

: 24827-66-5
1-methyl-1,3-dihydrobenzo[c]isothiazole-2,2-dioxide

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 6h;

Reference yield: 13.0%

: 1-diazo-N-methyl-N-phenylmethanesulfonamide

: 24827-66-5
1-methyl-1,3-dihydrobenzo[c]isothiazole-2,2-dioxide

Guidance literature:: With [(S)-(2-phenyl-4-pheox)Ru(CH₃CN)4]PF₆; In dichloromethane; at 20 ℃; for 20h; regioselective reaction; Inert atmosphere;
DOI:10.1016/j.tet.2020.131481

Reference yield:

: 89665-79-2
(2-chlorophenyl)-methanesulfonamide

: 24827-66-5
1-methyl-1,3-dihydrobenzo[c]isothiazole-2,2-dioxide

Guidance literature:: Multi-step reaction with 2 steps

1: 62 percent / potassium carbonate, copper-bronze powder / various solvent(s) / 3 h / 180 °C

2: 58 percent / NaOH / aq. ethanol / 18 h / Heating

With sodium hydroxide; copper; potassium carbonate; In ethanol;