3,5-Octanediol

Base Information

• Chemical Name: 3,5-Octanediol
• CAS No.: 24892-55-5
• Molecular Formula: C₈H₁₈O₂
• Molecular Weight: 146.23
• Mol file: 24892-55-5.mol

Synonyms:Octandiol-3,5;OCTANE-3,5-DIOL;3,5-Octanediol;

Chemical Property of 3,5-Octanediol

Chemical Property:

• Vapor Pressure: 0.005mmHg at 25°C
• PSA: 40.46000
• LogP: 1.30840

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,5-Octanediol

There total 6 articles about 3,5-Octanediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-hydroxy-octan-3-one (29649-20-5) + benzylamine (100-46-9) → 3,5-octanediol (24892-55-5,126628-20-4,126628-21-5,129025-63-4) + (4R,6R)-6-Benzylamino-octan-4-ol + (4S,6R)-6-Benzylamino-octan-4-ol

Guidance literature:

With 4 A molecular sieve; sodium cyanoborohydride; acetic acid; In tetrahydrofuran; at -15 ℃; for 24h; Yield given. Yields of byproduct given;

DOI:10.1016/S0040-4039(97)01349-X

Reference yield:

octane (111-65-9) → octane-4,5-diol (22607-10-9) + 2,5-octanediol (3214-15-1,4527-78-0) + 3,5-octanediol (24892-55-5)

Guidance literature:

Multi-step reaction with 2 steps

1: Bacillus megaterium glucose dehydrogenase; D-glucose; NADPH / aq. phosphate buffer / 2 h / 30 °C / Enzymatic reaction

2: Bacillus megaterium glucose dehydrogenase; D-glucose; NADPH / aq. phosphate buffer / 2 h / 30 °C / Enzymatic reaction

With D-glucose; Bacillus megaterium glucose dehydrogenase; NADPH; In aq. phosphate buffer;

DOI:10.1039/d0ob02086a

Reference yield:

octane (111-65-9) → octane-3,6-diol (24434-09-1) + 3,5-octanediol (24892-55-5) + 2,6-octanediol

Guidance literature:

Multi-step reaction with 2 steps

1: Bacillus megaterium glucose dehydrogenase; D-glucose; NADPH / aq. phosphate buffer / 2 h / 30 °C / Enzymatic reaction

2: Bacillus megaterium glucose dehydrogenase; D-glucose; NADPH / aq. phosphate buffer / 2 h / 30 °C / Enzymatic reaction

With D-glucose; Bacillus megaterium glucose dehydrogenase; NADPH; In aq. phosphate buffer;

DOI:10.1039/d0ob02086a

upstream raw materials:

octane

rac-3-octanol

octan-4-ol

5-hydroxy-octan-3-one

Refernces

• 1、 Haddad, Mansour,Dorbais, Jerome,Larcheveque, Marc. "Stereocontrolled reductive amination of 3-hydroxy ketones". . p. 5981 - 5984. Retrieved 2007/10/03.