22607-10-9

Basic information

• Product Name: 4,5-Octanediol
• Synonyms: 4,5-Octanediol;4,5-Octlen glycol;Octane-4,5-diol
• CAS NO: 22607-10-9
• Molecular Formula: C₈H₁₈O₂
• Molecular Weight: 146.23
• Mol File: 22607-10-9.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4,5-Octanediol(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-Octanediol(22607-10-9)
• EPA Substance Registry System: 4,5-Octanediol(22607-10-9)

Safety Data

• Hazardous Substances Data: 22607-10-9(Hazardous Substances Data)

Upstream product

• 71-36-3 butan-1-ol 
• 5455-24-3 octane-4,5-dione 
• 14850-23-8 trans-4-Octene 
• 589-62-8 octan-4-ol 
• 111-65-9 octane 
• 63364-38-5 3,3,6,6,9,9-hexaethyl-1,2,4,5,7,8-hexaoxacyclononane 
• 64-17-5 ethanol 
• 7642-15-1 (Z)-oct-4-ene 

Downstream Products

• 589-63-9 octan-4-one 
• 123-72-8 butyraldehyde 
• 5455-24-3 octane-4,5-dione 
• 592-99-4 4-octene 
• 133786-91-1 (4S,5R)-2-Phenyl-4,5-dipropyl-4,5-dihydro-1H-imidazole 
• 107-92-6 butyric acid 
• 1439-06-1 4,5-epoxyoctane 
• 496-77-5 butyroin 
• 343956-14-9 (+/-)-5-Phenoxyoctan-4-ol 

Relevant articles and documents

Biocatalytic synthesis of non-vicinal aliphatic diols

Biocatalysts are receiving increased attention in the field of selective oxyfunctionalization of C-H bonds, with cytochrome P450 monooxygenases (CYP450s), and the related peroxygenases, leading the field. Here we report on the substrate promiscuity of CYP505A30, previously characterized as a fatty acid hydroxylase. In addition to its regioselective oxyfunctionalization of saturated fatty acids (ω-1-ω-3 hydroxylation), primary fatty alcohols are also accepted with similar regioselectivities. Moreover, alkanes such as n-octane and n-decane are also readily accepted, allowing for the production of non-vicinal diols through sequential oxygenation. This journal is

Olefin-dependent discrimination between two nonheme HO-Fev=O tautomeric species in catalytic H2O2 epoxidations

A study was conducted to demonstrate olefin-dependent discrimination of two nonheme HO-Fev=O tautomeric species in catalytic H2O 2 epoxidations. Mechanistic studies were carried out under the condition of excess of olefin to minimize over-oxidation reactions and all reactions for the study were carried out under a N2 atmosphere to prevent auto-oxidation process due to presence of O2. It was observed that the diol/epoxide (D/E) ration for these reaction was dependent on the specific olefin and ranged from 3/2 (cyclooctene) to 6/1 (1-octene). The oxidation of cyclooctene using H218O2 revealed that only 28% of the oxygen atoms in the epoxide derived from H 2O2. Mechanistic results suggested that HO-Fe v=O oxidant need to be labeled before its reaction with substrates.

Diastereoselective reduction of acyclic hydroxyketones and diketones with an indium hydride reagent

Hydroxyketones and diketones have been reduced with lithium indium hydride to give meso-diols selectively. α-Hydroxyketones and α-diketones are reduced to meso-1,2-diols with high diastereoselectivities, whereas the selectivities of β-hydroxyketones and β-diketones are less satisfactory.