1H-Indole-5-carboxylic acid, 4-chloro-

Base Information

Chemical Name:1H-Indole-5-carboxylic acid, 4-chloro-
CAS No.:251107-41-2
Molecular Formula:C9H6ClNO2
Molecular Weight:195.60200
Hs Code.:
Mol file:251107-41-2.mol

Synonyms:4-chloroindole-5-carboxylic acid;4-chloro-indole-5-carboxylic acid;4-chloro-1H-indole-5-carboxylic acid;

Suppliers and Price of 1H-Indole-5-carboxylic acid, 4-chloro-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-Chloro-1H-indole-5-carboxylicacid 95+%
1g
$ 867.00

Chemenu
4-Chloro-1H-indole-5-carboxylicacid 95%
1g
$ 818.00

Alichem
4-Chloro-1H-indole-5-carboxylicacid
250mg
$ 1180.00

Alichem
4-Chloro-1H-indole-5-carboxylicacid
50mg
$ 432.30

Total 4 raw suppliers

Chemical Property of 1H-Indole-5-carboxylic acid, 4-chloro-

Chemical Property:

PSA：53.09000
LogP:2.51950

Purity/Quality:

98% ^*data from raw suppliers

4-Chloro-1H-indole-5-carboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1H-Indole-5-carboxylic acid, 4-chloro-

There total 6 articles about 1H-Indole-5-carboxylic acid, 4-chloro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: methyl 4-chloro-1H-indole-5-carboxylate

: 251107-41-2
4-chloro-indole-5-carboxylic acid

Guidance literature:: With sodium hydroxide; In methanol; water;

Reference yield:

: 1613730-03-2
methyl 4-amino-2-chloro-3-ethynylbenzoate

: 251107-41-2
4-chloro-indole-5-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: P(p-C₆H₄F)3; chloro(1,5-cyclooctadiene)rhodium(I) dimer / N,N-dimethyl-formamide / 0.83 h / 85 °C / Inert atmosphere

2: lithium hydroxide / methanol; water / 45 - 65 °C

With chloro(1,5-cyclooctadiene)rhodium(I) dimer; lithium hydroxide; P(p-C₆H₄F)3; In methanol; water; N,N-dimethyl-formamide;

Reference yield:

: 2457-76-3
4-amino-2-chlorobenzoic acid

: 251107-41-2
4-chloro-indole-5-carboxylic acid

Guidance literature:: Multi-step reaction with 5 steps

1.1: acetyl chloride / 5 h / Reflux

2.1: iodine; silver sulfate / ethanol / 0.25 h / Inert atmosphere

2.2: 1.5 h / 60 - 70 °C / Inert atmosphere

3.1: potassium carbonate / methanol / 0.25 h

4.1: P(p-C₆H₄F)3; chloro(1,5-cyclooctadiene)rhodium(I) dimer / N,N-dimethyl-formamide / 0.83 h / 85 °C / Inert atmosphere

5.1: lithium hydroxide / methanol; water / 45 - 65 °C

With chloro(1,5-cyclooctadiene)rhodium(I) dimer; iodine; potassium carbonate; silver sulfate; acetyl chloride; lithium hydroxide; P(p-C₆H₄F)3; In methanol; ethanol; water; N,N-dimethyl-formamide;