5-Bromo-3-methyl-2-furancarboxylic acid methyl ester

Base Information

• Chemical Name: 5-Bromo-3-methyl-2-furancarboxylic acid methyl ester
• CAS No.: 2528-01-0
• Molecular Formula: C7H7BrO3
• Molecular Weight: 219.035
• Hs Code.: 2932190090
• Mol file: 2528-01-0.mol

Synonyms:5-bromo-3-methyl-furan-2-carboxylic acid methyl ester;5-bromo-3-methylfuroate;Methyl 5-bromo-3-methyl-2-furoate;2-Furoic acid,5-bromo-3-methyl-,methyl ester;5-Brom-3-methyl-furan-2-carbonsaeure-methylester;

Chemical Property of 5-Bromo-3-methyl-2-furancarboxylic acid methyl ester

Chemical Property:

• Boiling Point: 236.4±35.0 °C(Predicted)
• PSA: 39.44000
• Density: 1.536±0.06 g/cm3(Predicted)
• LogP: 2.13710

Purity/Quality:

99% ^*data from raw suppliers

methyl5-bromo-3-methylfuran-2-carboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Bromo-3-methyl-2-furancarboxylic acid methyl ester

There total 5 articles about 5-Bromo-3-methyl-2-furancarboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

methyl 3-methylfuran-2-carboxylate (6141-57-7) → 5-bromo-3-methylfuran-2-carboxylic acid methyl ester (2528-01-0)

Guidance literature:

With bromine; In diethyl ether; at 20 ℃;

Reference yield:

acetylacetaldehyde dimethyl acetal (5436-21-5) → 5-bromo-3-methylfuran-2-carboxylic acid methyl ester (2528-01-0)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium tert-butylate / diethyl ether / -10 - 20 °C / Inert atmosphere

2: 4 h / 160 °C

3: bromine / dichloromethane / 0 °C

With potassium tert-butylate; bromine; In diethyl ether; dichloromethane;

DOI:10.1016/j.cclet.2020.09.023

Reference yield:

methyl 5,5-dimethoxy-3-methyl-2,3-epoxypentanoate (99183-76-3) → 5-bromo-3-methylfuran-2-carboxylic acid methyl ester (2528-01-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 4 h / 160 °C

2: bromine / dichloromethane / 0 °C

With bromine; In dichloromethane;

DOI:10.1016/j.cclet.2020.09.023

upstream raw materials:

methyl 3-methylfuran-2-carboxylate

acetylacetaldehyde dimethyl acetal

methyl 5,5-dimethoxy-3-methyl-2,3-epoxypentanoate

Downstream raw materials:

2-phenylthio-4-methylfuran

2-benzylthio-4-methylfuran

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 2528-01-0 5-Bromo-3-methyl-2-furancarboxylic acid methyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send