N-(1-Methyl-2-(4-phenethylpiperazino)ethyl)propionanilide oxalate (1:2)

Base Information

Chemical Name:N-(1-Methyl-2-(4-phenethylpiperazino)ethyl)propionanilide oxalate (1:2)
CAS No.:77563-02-1
Molecular Formula:2C₂H₂O₄*C₂₄H₃₃N₃O
Molecular Weight:559.616
Hs Code.:
DSSTox Substance ID:DTXSID80998774

Synonyms:N-(1-Methyl-2-(4-phenethylpiperazino)ethyl)propionanilide oxalate (1:2);77563-02-1;Propanamide, N-(1-methyl-2-(4-(2-phenylethyl)-1-piperazinyl)ethyl)-N-phenyl-, ethanedioate (1:2);DTXSID80998774;C24H33N3O.2C2H2O4;LS-119342;C24-H33-N3-O.2C2-H2-O4;Oxalic acid--N-phenyl-N-{1-[4-(2-phenylethyl)piperazin-1-yl]propan-2-yl}propanamide (2/1)

Suppliers and Price of N-(1-Methyl-2-(4-phenethylpiperazino)ethyl)propionanilide oxalate (1:2)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 0 raw suppliers

Chemical Property of N-(1-Methyl-2-(4-phenethylpiperazino)ethyl)propionanilide oxalate (1:2)

Chemical Property:

Vapor Pressure:8.96E-11mmHg at 25°C
Boiling Point:516.5°C at 760 mmHg
Flash Point:204.4°C
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:10
Exact Mass:559.25297977
Heavy Atom Count:40
Complexity:520

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(=O)N(C1=CC=CC=C1)C(C)CN2CCN(CC2)CCC3=CC=CC=C3.C(=O)(C(=O)O)O.C(=O)(C(=O)O)O

Technology Process of N-(1-Methyl-2-(4-phenethylpiperazino)ethyl)propionanilide oxalate (1:2)

There total 5 articles about N-(1-Methyl-2-(4-phenethylpiperazino)ethyl)propionanilide oxalate (1:2) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.4%

: 144-62-7,97993-78-7
oxalic acid

: 77563-01-0
N-<1-methyl-2-(4-phenethylpiperazino)ethyl>propionanilide

: 77563-02-1
N-[1-Methyl-2-(4-phenethyl-piperazin-1-yl)-ethyl]-N-phenyl-propionamide; compound with oxalic acid

Guidance literature:: In diethyl ether;
DOI:10.1248/cpb.28.3315

Reference yield:

: 5321-49-3
4-(phenethyl)piperazine

: 77563-02-1
N-[1-Methyl-2-(4-phenethyl-piperazin-1-yl)-ethyl]-N-phenyl-propionamide; compound with oxalic acid

Guidance literature:: Multi-step reaction with 5 steps

1: 16 g / benzene / 2 h / 5 °C

2: 68.2 percent / K₂CO₃ / ethanol / 10 h / Heating

3: 40.5 percent / LiAlH₄ / diethyl ether; tetrahydrofuran / 2 h / Heating

4: 51.6 percent / 2.5 h / 100 °C

5: 41.4 percent / diethyl ether

With lithium aluminium tetrahydride; potassium carbonate; In tetrahydrofuran; diethyl ether; ethanol; benzene;
DOI:10.1248/cpb.28.3315

Reference yield:

: 77563-26-9
1-(2-anilinopropionyl)-4-phenethylpiperazine

: 77563-02-1
N-[1-Methyl-2-(4-phenethyl-piperazin-1-yl)-ethyl]-N-phenyl-propionamide; compound with oxalic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 40.5 percent / LiAlH₄ / diethyl ether; tetrahydrofuran / 2 h / Heating

2: 51.6 percent / 2.5 h / 100 °C

3: 41.4 percent / diethyl ether

With lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether;
DOI:10.1248/cpb.28.3315