1-(1-Naphthylsulfonyl)piperidine

Base Information

Chemical Name:1-(1-Naphthylsulfonyl)piperidine
CAS No.:252985-50-5
Molecular Formula:C₁₅H₁₇NO₂S
Molecular Weight:275.371
Hs Code.:
DSSTox Substance ID:DTXSID60359420
Nikkaji Number:J3.569.761F
Wikidata:Q82140623
ChEMBL ID:CHEMBL1299498
Mol file:252985-50-5.mol

Synonyms:1-(1-naphthylsulfonyl)piperidine;252985-50-5;1-naphthalen-1-ylsulfonylpiperidine;Piperidine, 1-(1-naphthalenylsulfonyl)-;a-naphthylsulfonyl piperidine;Oprea1_202000;MLS001147080;SCHEMBL1063351;CHEMBL1299498;DTXSID60359420;HMS1651P02;HMS2984J14;AKOS002286027;WAY-270598;SMR000673163;AQ-390/13304212;SR-01000009288;SR-01000009288-1;Z57379936

Suppliers and Price of 1-(1-Naphthylsulfonyl)piperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 0 raw suppliers

Chemical Property of 1-(1-Naphthylsulfonyl)piperidine

Chemical Property:

PSA：45.76000
LogP:4.03310
XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:275.09799996
Heavy Atom Count:19
Complexity:395

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(CC1)S(=O)(=O)C2=CC=CC3=CC=CC=C32

Technology Process of 1-(1-Naphthylsulfonyl)piperidine

There total 6 articles about 1-(1-Naphthylsulfonyl)piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 35856-62-3
1-piperidinesulfonyl chloride

: 91-20-3,71998-51-1,72931-45-4
naphthalene

: 71862-59-4
1-(naphthalene-2-sulfonyl)-piperidine

: 252985-50-5
1-(naphthalen-1-ylsulfonyl)piperidine

Guidance literature:: With In(OSO₂CF₃)3; In 1,2-dichloro-ethane; at 100 ℃; for 24h;
DOI:10.1055/s-2002-34907

Reference yield:

: bis(1-naphthyl)iodonium tetrafluoroborate

: 252985-50-5
1-(naphthalen-1-ylsulfonyl)piperidine

Guidance literature:: Multi-step reaction with 2 steps

1: iron(III) chloride; sodium hydroxymethanesulfinate dihydrate / N,N-dimethyl-formamide; acetonitrile / 0.33 h / 20 °C

2: N-chloro-succinimide; triethylamine / 2.5 h / 0 - 23 °C

With iron(III) chloride; N-chloro-succinimide; sodium hydroxymethanesulfinate dihydrate; triethylamine; In N,N-dimethyl-formamide; acetonitrile;
DOI:10.1039/c5cc09830k

Reference yield:

: 90-14-2
1-Iodonaphthalene

: 252985-50-5
1-(naphthalen-1-ylsulfonyl)piperidine

Guidance literature:: Multi-step reaction with 3 steps

1.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 20 °C

1.2: 20 °C

2.1: iron(III) chloride; sodium hydroxymethanesulfinate dihydrate / N,N-dimethyl-formamide; acetonitrile / 0.33 h / 20 °C

3.1: N-chloro-succinimide; triethylamine / 2.5 h / 0 - 23 °C

With iron(III) chloride; N-chloro-succinimide; sodium hydroxymethanesulfinate dihydrate; triethylamine; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1039/c5cc09830k