35856-62-3

Usage

Uses

Piperidine-1-sulfonyl chloride is used as pharmaceutical intermediate.

InChI:InChI=1/C5H10ClNO2S/c6-10(8,9)7-4-2-1-3-5-7/h1-5H2

Upstream product

• 110-89-4 piperidine 
• 2156-71-0 N-chloropiperidine 
• 6091-44-7 piperidine hydrochloride 
• 110-85-0 piperazine 
• 16475-29-9 phenylchlorosulfate 

Downstream Products

• 100391-95-5 piperidine-1-sulfonic acid-(4-formyl-phenyl ester) 
• 1020-49-1 N-(phenoxysulfonyl)-piperidine 
• 72119-31-4 N-(4-phenylphenoxysulfonyl)-piperidine 
• 71862-59-4 1-(naphthalene-2-sulfonyl)-piperidine 
• 252985-50-5 1-(naphthalen-1-ylsulfonyl)piperidine 
• 35088-89-2 1-(4-methoxybenzenesulfonyl)-piperidine 
• 501411-82-1 1-(2-methoxy-benzenesulfonyl)-piperidine 
• 4703-22-4 N-tosylpiperidine 
• 692755-62-7 4β-(1-piperidino)sulfonamido-4'-tert-butyldimethylsilyloxy-4'-O-demethyl-4-desoxypodophyllotoxin 
• 727989-51-7 Piperidine-1-sulfonic acid (4-{2-[(R)-5-(3-chloro-phenyl)-2-oxo-oxazolidin-3-yl]-ethyl}-phenyl)-amide 
• 454219-01-3 piperidine-1-sulfonic acid (4-{2-[5(R)-(3-chloro-phenyl)-2-oxo-oxazolidin-3-yl]-2-methyl-propyl}-phenyl)-amide 
• 2851-09-4 2-(piperidin-1-yl)-1,3-benzoxazole 
• 515172-79-9 (1S,2S)-N-(piperidyl-N-sulfonyl)-1,2-diphenylethylenediamine 
• 105168-75-0 N-[2-Chloro-4-(piperidine-1-sulfonylamino)-phenyl]-acetamide 

Relevant academic research and scientific papers

REACTIONS OF SULPHURYL FLUORIDE, SULPHURYL CHLOROFLUORIDE AND SULPHURYL CHLORIDE WITH AMINES

The reactions of sulphuryl fluoride, sulphuryl chlorofluoride and sulphuryl chloride with the amines tert-butylamine, benzylamine, piperidine, pyridine and quinoline have been investigated.The primary and secondary amines react with the elimination of hydrogen halides and formation of S-N bonds whereas tertiary amines form 1:2 adducts.

Sulfonamide derivatives of cis-imidazolines as potent p53-MDM2/MDMX protein-protein interaction inhibitors

p53-MDM2/MDMX interaction inhibitors represent the prospective agents for targeted anticancer therapy in tumors expressing wild-type p53 protein. Imidazoline-based MDM2-targeted inhibitors of such type, nutlins, contain halogen-substituted phenyl rings, w

Nickel-Catalyzed Hydrodeoxygenation of Aryl Sulfamates with Alcohols as Mild Reducing Agents

The nickel-catalyzed hydrodeoxygenation of aryl sulfamates has been developed with alcohols as mild reductants. A variety of functional groups and heterocycles were tolerated in this reaction system to give the desired products in high yields. In addition, the gram-scale process and stepwise cine-substitution were also achieved with high efficiency.

S(vi) in three-component sulfonamide synthesis: Use of sulfuric chloride as a linchpin in palladium-catalyzed Suzuki-Miyaura coupling

Sulfuric chloride is used as the source of the -SO2- group in a palladium-catalyzed three-component synthesis of sulfonamides. Suzuki-Miyaura coupling between the in situ generated sulfamoyl chlorides and boronic acids gives rise to diverse sulfonamides in moderate to high yields with excellent reaction selectivity. Although this transformation is not workable for primary amines or anilines, the results show high functional group tolerance. With the solving of the desulfonylation problem and utilization of cheap and easily accessible sulfuric chloride as the source of sulfur dioxide, redox-neutral three-component synthesis of sulfonamides is first achieved. This journal is

Triazole compounds and their use in agriculture (by machine translation)

The present invention provides a triazole compound and its application in agriculture; in particular, the invention provides compounds of formula (A) indicated by the compound and its preparation method; the composition containing these compounds and preparation and their use as fungicides; wherein R1 , R2 , R3 , W, R4 , R5 , R6 , R7 , R8 , R9 , Ra , Rb And in the event of x has the meanings given by the invention. (by machine translation)

PREPARATION OF COBICISTAT INTERMEDIATES

The present disclosure provides crystalline piperidine sulfamoyl intermediates of formula 8 and 9. The present disclosure also relates to an improved process for the preparation of cobicistat using compounds of formulae 8 and 9.

Synthesis of aryl sulfonamides via palladium-catalyzed chlorosulfonylation of arylboronic acids

A palladium-catalyzed method for the preparation of sulfonamides is described. The process exhibits significant functional group tolerance and allows for the preparation of a number of arylsulfonyl chlorides and sulfonamides under mild conditions.

OXYCARBAMOYL COMPOUNDS AND THE USE THEREOF

The invention relates to oxycarbamoyl compounds of Formula I: The invention is also directed to the use compounds of Formula I to treat, prevent or ameliorate a disorder responsive to the blockadeof calcium channels, and particularly N-type calcium channe

Inhibitors of HCV NS5B polymerase: Synthesis and structure-activity relationships of N-alkyl-4-hydroxyquinolon-3-yl-benzothiadiazine sulfamides

Substituted N-alkyl-4-hydroxyquinolon-3-yl-benzothiadiazine sulfamides were investigated as inhibitors of genotype 1 HCV polymerase. Structure-activity relationship patterns for this class of compounds are discussed.

NOVEL COMPOUNDS AS INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE

The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.