Benzene, 1-(1-bromo-2,2-diphenylethenyl)-4-methoxy-

Base Information

• Chemical Name: Benzene, 1-(1-bromo-2,2-diphenylethenyl)-4-methoxy-
• CAS No.: 25354-48-7
• Molecular Formula: C21H17BrO
• Molecular Weight: 365.269
• DSSTox Substance ID: DTXSID70441603
• Nikkaji Number: J306.310K
• Mol file: 25354-48-7.mol

Synonyms:Benzene, 1-(1-bromo-2,2-diphenylethenyl)-4-methoxy-;25354-48-7;DTXSID70441603;1,1-Diphenyl-2-(4-methoxyphenyl)-2-bromoethene

Chemical Property of Benzene, 1-(1-bromo-2,2-diphenylethenyl)-4-methoxy-

Chemical Property:

• XLogP3: 6.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 364.04628
• Heavy Atom Count: 23
• Complexity: 363

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C(=C(C2=CC=CC=C2)C3=CC=CC=C3)Br

Technology Process of Benzene, 1-(1-bromo-2,2-diphenylethenyl)-4-methoxy-

There total 7 articles about Benzene, 1-(1-bromo-2,2-diphenylethenyl)-4-methoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

2,2-diphenyl-1-(4-methoxyphenyl)ethylene (18648-74-3) → 1-bromo-1-(p-methoxyphenyl)-2,2-diphenylethene (25354-48-7)

Guidance literature:

With bromine; In chloroform; at 20 ℃; Inert atmosphere;

DOI:10.1016/j.tet.2012.06.096

Reference yield: 41.0%

1,1-dibromo-2,2-diphenylethylene (2592-73-6) + 4-methoxyphenylboronic acid (5720-07-0) → 1-bromo-1-(p-methoxyphenyl)-2,2-diphenylethene (25354-48-7)

Guidance literature:

With trifuran-2-yl-phosphane; caesium carbonate; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In tetrahydrofuran; diethyl ether; water; for 18h; Inert atmosphere; Schlenk technique; Reflux;

DOI:10.1021/acs.joc.5b01693

Reference yield:

1-(4-methoxyphenyl)-2,2-diphenylethanone (1889-74-3) → 1-bromo-1-(p-methoxyphenyl)-2,2-diphenylethene (25354-48-7)

Guidance literature:

With phosphorus tribromide; N,N-dimethyl-formamide; In dichloromethane; for 72h; Heating;

DOI:10.1021/jo9603441

upstream raw materials:

2,2-diphenyl-1-(4-methoxyphenyl)ethylene

1-(4-methoxyphenyl)-2,2-diphenylethanone

2-(4-methoxyphenyl)-1,1-diphenylethan-1-ol

bromine

Downstream raw materials:

2,2-diphenyl-1-(4-methoxyphenyl)ethylene

1-methoxy-1-(p-methoxyphenyl)-2,2-diphenylethene

1-(p-methoxyphenyl)-2,2-diphenyl-1-propoxyethene

1-(4-methoxyphenyl)-2,2-diphenylethanone