Phosphonic acid, [(methylsulfonyl)methyl]-, dimethyl ester

Base Information

• Chemical Name: Phosphonic acid, [(methylsulfonyl)methyl]-, dimethyl ester
• CAS No.: 25508-33-2
• Molecular Formula: C₄H₁₁O₅PS
• Molecular Weight: 202.168
• Mol file: 25508-33-2.mol

Synonyms:Dimethylmethylsulfonomethanphosphonat;[(methylsulfonyl)methyl]-phosphonic acid dimethyl ester;Methanesulfonylmethyl-phosphonic acid dimethyl ester;dimethyl methylsulfonylmethylphosphonate;

Chemical Property of Phosphonic acid, [(methylsulfonyl)methyl]-, dimethyl ester

Chemical Property:

• Melting Point: 82 °C
• Boiling Point: 354.1±25.0 °C(Predicted)
• PSA: 87.86000
• Density: 1.325±0.06 g/cm3(Predicted)
• LogP: 1.55520

Purity/Quality:

dimethyl(methanesulfonylmethyl)phosphonate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of Phosphonic acid, [(methylsulfonyl)methyl]-, dimethyl ester

There total 1 articles about Phosphonic acid, [(methylsulfonyl)methyl]-, dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ dimethyl <(methylsulfonyl)methyl>phosphonate (25508-33-2)

Guidance literature:

1, KMnO4;

Reference yield:

C28H27FN4O3 (1152320-85-8) + dimethyl <(methylsulfonyl)methyl>phosphonate (25508-33-2) → C30H31FN4O4S (1152320-86-9)

Guidance literature:

With lithium hexamethyldisilazane;

Reference yield:

dimethyl <(methylsulfonyl)methyl>phosphonate (25508-33-2) + Boc-L-phenylalaninal (72155-45-4) → (3S,E)-3-(tert-butoxycarbonylamino)-4-phenyl-1-methylsulfonyl-1-butene (99281-93-3)

Guidance literature:

With sodium hydride; Yield given. Multistep reaction; 1.) THF, 30 min, 2.) THF, 1.5 h;

DOI:10.1021/jm00151a018

Downstream raw materials:

(3S,E)-3-(tert-butoxycarbonylamino)-4-phenyl-1-methylsulfonyl-1-butene

C₃₀H₃₁FN₄O₄S

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